Gene ML1316
in Mycobacterium leprae TN
General annotation
| Type | CDS |
| Function | Unknown |
| Product | Probable mycobacterium proteasome ATPase Mpa |
| Comments | ML1316, len: 609 aa. Probable mpa, mycobacterium proteasome ATPase (see Darwin et al., 2003) Highly similar to Mycobacterium tuberculosis mpa, proteasome ATPase Rv2115c SW:YL15_MYCTU (O33250) (609 aa), Fasta scores: E(): 0, 92.8% identity in 609 aa overlap. And many AAA ATPase-family proteins including: Rhodococcus erythropolis ARC protein TR:O50202 (EMBL:AF088800) (591 aa), Fasta scores: E(): 0, 81.8% identity in 588 aa overlap, Methanococcus jannaschii cell division cycle protein SW:YB56_METJA (Q58556) (903 aa), Fasta scores: E(): 1.6e-17, 46.8% identity in 250 aa overlap. Contains possible coiled-coils between residues 76..98. Contains Pfam match to entry PF00004 AAA, ATPases associated with various cellular activities (AAA). Contains PS00017 ATP/GTP-binding site motif A (P-loop). Contains PS00674 AAA-protein family signature. |
| Functional category | Cell wall and cell processes |
| Mutant | Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 1568248 | 1570077 | + |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium leprae TN|ML1316|mpa
VGESERSEAFNPPREAGMSSGDIAELEQLRREIVVLREQLEHAVGPHGSVRSVRDVHQLEARIDSLTARNSKLMDTLKEARQQLLALREEVDRLGQPPSGYGVLLAAHDDETVDVFTSGRKMRLTCSPNIEVASLRKGQTVRLNEALTVVEAGTFEAVGEVSTLREVLADGHRALVVGHADEERIVCLAEPLVAENLLDGVPGALNDDSRPRKLRPGDSLLVDPKAGYAFERVPKAEVEDLVLEEVPDVSYQDIGGLTRQIEQIRDAVELPFLHKELYREYALRPPKGVLLYGPPGCGKTLIAKAVANSLAKKMAEVRGDDAREAKSYFLNIKGPELLNKFVGETERHIRLIFQRAREKASEGTPVIVFFDEMDSIFRTRGTGVSSDVETTVVPQLLSEIDGVEGLENVIVIGASNREDMIDPAILRPGRLDVKIKIERPDAEAAQDIYSKYLTESLPVHADDLTEFDGDRAACIKAMIEKVVDRMYAEIDDNRFLEVTYANGDKEVMYFKDFNSGAMIQNVVDRAKKNAIKSVLETGQPGLRIQHLLDSIVDEFAENEDLPNTTNPDDWARISGKKGERIVYIRTLVTGKSSSASRAIDTESNLGQYL
Bibliography
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