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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
General annotation
TypeCDS
FunctionUnknown
Productproteasome (beta subunit) PrcB
CommentsML1322, len: 291 aa. Probable prcB, proteasome beta-type subunit 2 (EC 3.4.25.1). Highly similar to many proposed 20S proteasome beta subunits including: Methanococcus jannaschii SW:PRCB_METJA (Q58634) (224 aa), Fasta scores: E(): 0.00015, 29.0% identity in 183 aa overlap, Rhodococcus sp. TR:Q53079 (EMBL:U26421) (294 aa), Fasta scores: E(): 0, 63.5% identity in 266 aa overlap and Mycobacterium tuberculosis Rv2110c TR:O33245 (EMBL:Z97559) (291 aa), Fasta scores: E(): 0, 81.0% identity in 290 aa overlap. Contains Pfam match to entry PF00227 proteasome, Proteasome A-type and B-type.
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS15756851576560+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
       
Protein sequence
>Mycobacterium leprae TN|ML1322|prcB
VTRSFPDRLPTNLAFPGISVINQSSFVDLLRRQAPELLPVSLGGGQSGGGQQLSHGTTIVVLKYPGGVVIAGDRRSTQGNMIAGRDVRKVYITDDYTATGIAGIAAVAVEFARLYAVELEHYEKLEGVPLTFAGKVNRLAIMVRSNLTAAMQGLLALPLLAGYDIHAPDPQSAGRIVSFDAAGGWNIEEEGYQSVGSGSIFAKSSIKKLYSQVSDADSALRVAIEALYDAADDDSATGGPDLVRGIYPTAVTIGAEGAAEVTESRIAELAREIIESRSRAYTLGSFGGSEK
      
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