Gene ML1328 in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namepaf
Gene length1359 bp
IdentifierML1328
Location 1579805 bp
Protein summary information
Molecular mass51426.1 Da
Isoelectric point6.84
Protein length453 amino acids
Structural information
PFAMPF03136, PF03316
Orthologs
M. tuberculosis H37RvRv2097c
M. lepromatosis Mx1-22AMLPM_1328
Cross-references
UniProtP54077
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductProbable proteasome associated factor Paf
CommentsML1328, len: 452 aa. Probable paf, proteasome associated factor (see Darwin et al., 2003). Highly similar to Mycobacterium tuberculosis Rv2097c SW:YK97_MYCTU (Q10706) paf, proteasome associated factor (452 aa), Fasta scores: E(): 0, 94.9% identity in 452 aa overlap. And many proteins of unknown function including: Rhodococcus erythropolis TR:P72263 (EMBL:Z82004) (447 aa), Fasta scores: E(): 0, 89.3% identity in 447 aa overlap. Contains a putative helix-turn-helix motif situated between residues 380..401 (+3.12 SD). Contains a probable helix-turn-helix motif at aa 380-401 (Score 1155, SD +3.12).
Functional categoryCell wall and cell processes, Intermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS15798051581163+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML1328|paf
VQRRIMGIETEFGVTCTFHGHRRLSPDEVARYLFRRVVSWGRSSNVFLRNGARLYLDVGSHPEYATAECDNLVQLVTHDRAGEWVLEDLLVDAEQRLADEGIGGDIYLFKNNTDSAGNSYGCHENYLIVRAGEFSRISDVLLPFLVTRQLICGAGKVLQTPKAATFCLSQRAEHIWEGVSSATTRSRPIINTRDEPHADAEKYRRLHVIVGDSNMCETTTMLKVGTAALMLEMVETGVPFRDFSLDNPIRAIREVSHDITGRRPVRLAGGRQASALDIQREYYTRAFEHLQTREPNVQFEQVVDLWGRQLDAIESQDFAKVDTEIDWVIKRKLFQRYQDRDNMELTDPKIAQLDLAYHDIKRGRGVFDLLQRKGLAARVTTDEDIADAVNHPPQTTRARLRGEFISAAQAAGRDFTVDWVHLKLNDQAQRTVLCKDPFRAVDERVKRLIASM
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