Gene ML1339c in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameML1339c
Gene length1578 bp
IdentifierML1339c
Location 1596795 bp
Protein summary information
Molecular mass54245.1 Da
Isoelectric point6.42
Protein length526 amino acids
Structural information
PFAMPF00561, PF08386
Orthologs
M. tuberculosis H37RvRv2672
M. lepromatosis Mx1-22AMLPM_1339
Cross-references
UniProtQ7AQ63
Gene OntologyPeptidase activity
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductPOSSIBLE SECRETED PROTEASE
CommentsML1339c, len: 525 aa. Possible secreted protease. Highly similar to several proteases including: Streptomyces lividans TR:Q54399 (EMBL:L42759) (513 aa), Fasta scores: E(): 2.7e-19, 25.7% identity in 548 aa overlap and Mycobacterium tuberculosis Rv2672 TR:P71969 (EMBL:Z80225) (528 aa), Fasta scores: E(): 0, 74.4% identity in 528 aa overlap. Contains a possible N-terminal signal sequence.
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS15967951598372-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML1339c|ML1339c
MATVVGMRWHTRSATILVAVTALLVGCVPGLAANPRFATNSGARPQGAAATTTPAAGPLLIAAPKKDLSWHDCTSRLFRDAGVAAAPGIQLECADYDSDLDPVNGGSGTVTIGAVRARSSQTPRDAGPLVFTTGSDLPSSAQLPVWLSRSGADVVRTHPIVAVDRRGIGMSNPIDCRDHYDRQKMRDQAQFESGDDPVANLSDISNTATTNCTDAITPGTSAYDNSHAASDIERLRNLWDVPALALIGIGNGAEVALAYAASRPDRVARLILDSPIALGIKTEAAAEQQVRGQQAALDTFAAQCVALKCALGPDPKSAVTALLAAAHAGKGPGGASVAAVTNAITVSLGFPSGDRVGTTMSLANALAAARSGDANPLTNLIHRSDATQDSDGQFVNDCSDALNRPTPDRVRELVVAWGKLYPEFGTVGALNLVKCVHWPTGTTPQPPKNLKIDVMVLDVQNDPIVGFEGVAATTAAIINANAASKRVMWQGIGHGASIYSACAVPPIIGYLTSGKLPATDTYCPA
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