Gene ML1359 in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameppnK
Gene length936 bp
IdentifierML1359
Location 1618919 bp
Protein summary information
Molecular mass33186.1 Da
Isoelectric point5.74
Protein length312 amino acids
Structural information
PFAMPF01513
Orthologs
M. tuberculosis H37RvRv1695
M. lepromatosis Mx1-22AMLPM_1359
Cross-references
UniProtQ49897
Gene OntologyNad+ kinase activity, Cytoplasm, Metabolic process, Metal ion binding, Atp binding
Enzyme Classification2.7.1.23
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductInorganic polyphosphate/ATP-NAD kinase PpnK (Poly(P)/ATP NAD kinase)
CommentsML1359, len: 311 aa. Probable ppnK, Inorganic polyphosphate/ATP-NAD kinase (EC 2.7.1.23). Similar to many others including: Streptomyces coelicolor TR:Q9S219 (EMBL:AL109848) (301 aa), Fasta scores: E(): 0, 54.5% identity in 303 aa overlap and Mycobacterium tuberculosis Rv1695 SW:YG95_MYCTU (O33196) (307 aa), Fasta scores: E(): 0, 87.9% identity in 305 aa overlap. Contains Pfam match to entry PF01513 DUF15, Domain of unknown function.
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS16189191619854+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML1359|ppnK
VTPRKAAQRTVLLVVHTGRDEATETARRVKKIVGDNGIALRVLSAEAVDRGSLHLALDNMRAMGVDIEVVDADPHVAQGCELVLVLGGDGTFLRAAELARTARIPVLGVNLGRIGFLAEAEAEAIDVVLEHVIARSYRVEERLTLDIVVRQGGNIIDQGWALNEASLEKGPRLGVLGVVVEIEGRPVSTFGCDGVLVSTPTGSTAYAFSAGGPVLWPDLEAILVVPNNAHALFGRPMVTSPDATVAIELEANGNDALVFCDGRREMIIPAGGRLEVTRCATPVKWARLDSAPFTDRLVSKFRLPVTGWRGK
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