Gene ML1372 in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameengA
Gene length1389 bp
IdentifierML1372
Location 1631874 bp
Protein summary information
Molecular mass50207.2 Da
Isoelectric point8.69
Protein length463 amino acids
Structural information
PFAMPF01926
Orthologues
M. tuberculosisRv1713
Cross-references
UniProtQ49884
Gene OntologyIntracellular, Gtp binding
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE GTP-BINDING PROTEIN ENGA
CommentsML1372, len: 462 aa. Probable engA, GTP-binding protein. Highly similar to many proposed Era/ThdF family GTP-binding proteins including: Bacillus subtilis SW:ENGA_BACSU (P50743) (436 aa), Fasta scores: E(): 0, 41.0% identity in 434 aa overlap and Mycobacterium tuberculosis Rv1713 SW:ENGA_MYCTU (O33212) (463 aa), Fasta scores: E(): 0, 88.6% identity in 463 aa overlap. Contains Pfam match to entry PF01926 MMR_HSR1, GTPase of unknown function. Contains 2 x PS00017 ATP/GTP-binding site motif A (P-loop).
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS16318741633262+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML1372|engA
VVSQDGTWSDESDWELDDSDLAEFGPVVAVVGRPNVGKSTLVNRILGRREAVVQDVPGVTRDRVSYDAMWTGRRFVVQDTGGWEPDAKGLKRLVAEQASVAMRTADAVILVVDVGVGATDADEAAARILLRSGKLVFLAANKVDGEKGESDASALWSLGLGEPHAISAMHGRGVADLLDKVLAALPNVAESTSLDGGLRRVALVGKPNVGKSSLLNKLAGDQRSVVHEAAGTTVDPVDSLIEMGGRVWRFVDTAGLRRKVGQASGHEFYASVRTHGAIDSAEVVIMLIDASEPLTGQDQRVLSMVIDAGRALVLAFNKWDLVDEDRCDLLEREIDRELVQVRWAQRVNISAKTGRAVQKLVPAMENSLASWDTRIATGPLNIWIKAVVAATPPPVRGGKQPRILFATQATARPPTFVLFTTGFLEACYRRFLERRLRETFGFEGSPIRINVRVREKRGLKRR
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