Gene ML1391c in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameML1391c
Gene length699 bp
IdentifierML1391c
Location 1667505 bp
Protein summary information
Molecular mass24825.8 Da
Isoelectric point4.57
Protein length233 amino acids
Structural information
PFAMPF00753
Orthologs
M. tuberculosis H37RvRv1637c
M. lepromatosis Mx1-22AMLPM_1391
Cross-references
UniProtQ9CC25
Gene OntologyHydrolase activity
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
Productconserved hypothetical protein
CommentsML1391c, len: 232 aa. Conserved hypothetical protein. Similar to several including: Streptomyces coelicolor putative hydrolase TR:Q9Z505 (EMBL:AL035591) (218 aa), Fasta scores: E(): 0, 50.9% identity in 224 aa overlap and in parts to Rhodopseudomonas blastica probable hydroxyacylglutathione hydrolase SW:GLO2_RHOBL (P05446) (255 aa), Fasta scores: E(): 2.4e-08, 37.9% identity in 145 aa overlap. Also similar to Mycobacterium tuberculosis hypothetical protein Rv1637c TR:O06154 (EMBL:Z95554) (264 aa), Fasta scores: E(): 0, 84.0% identity in 231 aa overlap. Contains Pfam match to entry PF00753 lactamase_B, Metallo-beta-lactamase superfamily.
Functional categoryConserved hypotheticals
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS16675051668203-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML1391c|ML1391c
MTASIDPVNDYTGHVDPGTAARRALPGATILKVSVGPMDNNAYLVTCSATGETLLIDAANDAEVLIDLVQRYAPKLSLIVTSHQHFDHWQALEAVVAATGAPTAVHELDAEPLPVRPDRLLTNGDCVQIGELTFDVIHLRGHTPGSIALALDGATSGPKTGRVTQLFTGDCLFPGGVGKTWQRSDFTQLLDDVTTRVFDVYADTTAIYPGHGDDTVLGAERPSLAEWRERGW
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