Gene ML1394 in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameinfC
Gene length558 bp
IdentifierML1394
Location 1675811 bp
Protein summary information
Molecular mass20463.1 Da
Isoelectric point9.33
Protein length186 amino acids
Structural information
PFAMPF00707, PF05198
Orthologs
M. tuberculosis H37RvRv1641
M. lepromatosis Mx1-22AMLPM_1394
Cross-references
UniProtQ9CC22
Gene OntologyTranslation initiation factor activity, Translational initiation, Cytoplasm
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE INITIATION FACTOR IF-3 INFC
CommentsML1394, len: 185 aa. Probable infC, initiation factor IF-3. Highly similar to many translation initiation factors (3) including: Neisseria meningitidis TR:AAF41134 (EMBL:AE002426) (155 aa), Fasta scores: E(): 3.8e-28, 48.7% identity in 152 aa overlap, Bacillus subtilis SW:IF3_BACSU (P55872) (171 aa), Fasta scores: E(): 1.4e-26, 48.7% identity in 150 aa overlap and Mycobacterium tuberculosis Rv1641 SW:IF3_MYCTU (P94975) (201 aa), Fasta scores: E(): 0, 89.2% identity in 185 aa overlap. Contains Pfam match to entry PF00707 IF3, Translation initiation factor IF-3. Contains PS00938 Initiation factor 3 signature.
Functional categoryInformation pathways
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS16758111676368+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML1394|infC
LIGPGGEQVGIVRIEDALRVAADADLDLVEVAPNARPPVCKIMDYGKYKYEVAQKARESRRNQQQTVVKEQKLRPKIDDHDYETKKSHVVRFLEAGSKVKVTIMFRGREQSRPELGYRLLQRLGADVADYGFVETSAKQDGRNMTMVLAPHRGAKTRASARHPEVPGAGSVQDIDATGDTDGSPH
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