Gene ML1401 in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namepheS
Gene length1053 bp
IdentifierML1401
Location 1681041 bp
Protein summary information
Molecular mass38533.5 Da
Isoelectric point5.12
Protein length351 amino acids
Structural information
PFAMPF01409, PF02912
Orthologs
M. tuberculosis H37RvRv1649
M. lepromatosis Mx1-22AMLPM_1401
Cross-references
UniProtQ9CC17
Gene OntologyCytoplasm, Magnesium ion binding, Phenylalanine-trna ligase activity, Phenylalanyl-trna aminoacylation, Atp binding
Enzyme Classification6.1.1.20
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductProbable phenylalanyl-tRNA synthetase, alpha chain PheS
CommentsML1401, len: 350 aa. Probable pheS, phenylalanyl-tRNA synthetase, alpha chain (EC 6.1.1.20). Highly similar to many phenylalanyl-tRNA synthetase alpha chains including: Escherichia coli SW:SYFA_ECOLI (P08312) (327 aa), Fasta scores: E(): 0, 45.9% identity in 331 aa overlap and Mycobacterium tuberculosis Rv1649 TR:P94984 (EMBL:Z85982) (341 aa), Fasta scores: E(): 0, 85.0% identity in 341 aa overlap. Contains Pfam match to entry PF01409 tRNA-synt_2d, tRNA synthetases class II (F). Contains PS00179 Aminoacyl-transfer RNA synthetases class-II signature 1.
Functional categoryInformation pathways
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS16810411682093+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML1401|pheS
VGDQPVDLSMLSSEALAKAVNTARQAIALAVNLDALALIKAEHLGDRSPLALARQALASLPKIDRAAVGKQVNTARSEVQRDYDERLATLQAERDAAVLVTERIDVTLPSTRQPTGARHPITILAEHIADTFIAMGWELVDGPEVETEQFNFDALNFPADHPARSEQDTFYIAPDGSRQLLRTHTSPVQVRTLLERELPVYVISIGRAFRTDEVDATHTPVFHQVEGLAVDRGLSMAHLRGTLDIFARAEFGPSTRTRIRPHFFPFTEPSAEVDVWFASKKDGADWVEWGGCGMVHPNVLRATGIDPDIYSGFAFGMGLERTLQFRNSIPNMRDMVEGDVRFSLPFGVGA
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