Gene ML1409 in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameargD
Gene length1215 bp
IdentifierML1409
Location 1690893 bp
Protein summary information
Molecular mass42007.1 Da
Isoelectric point5.91
Protein length405 amino acids
Structural information
PFAMPF00202
Orthologs
M. tuberculosis H37RvRv1655
M. lepromatosis Mx1-22AMLPM_1409
Cross-references
UniProtQ9CC12
Gene OntologyArginine biosynthetic process, Cytoplasm, Pyridoxal phosphate binding, N2-acetyl-l-ornithine:2-oxoglutarate 5-aminotransferase activity
Enzyme Classification2.6.1.11
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductProbable Acetylornithine aminotransferase ArgD
CommentsML1409, len: 404 aa. Probable argD, Acetylornithine aminotransferase (EC 2.6.1.11). Highly similar to many acetylornithine aminotransferases (EC 2.6.1.11) involved in arginine biosynthesis, including: Escherichia coli SW:ARGD_ECOLI (P18335) (405 aa), Fasta scores: E(): 0, 38.7% identity in 390 aa overlap and Mycobacterium tuberculosis Rv1655 SW:ARGD_MYCTU (P94990) (400 aa), Fasta scores: E(): 0, 82.9% identity in 397 aa overlap. Contains Pfam match to entry PF00202 aminotran_3, Aminotransferases class-III pyridoxal-phosphate. Contains PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. Belongs to class-III of pyridoxal-phosphate-dependent aminotransferases.
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS16908931692107+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML1409|argD
MTPTQTNTATMQQRWETVMMNNYGTPPIVLASGNGAVVTDVDSNTYLDLLGGIAVNVLGHRHPAVIEAVTHQITTLGHTSNLYATEPSITLAEELVALLGADTQTRVFFCNSGTEANELAFKLSRLTGRTKLVAAQAAFHGRTMGSLALTGQPAKQAAFEPLPGHVTHVPYGQVDALAAAVDNDTAAVFLEPIMGESGVIVPPEGYLAAARDITTRHGALLVIDEVQTGIGRTGAFFAHQHDSITPDVVTLAKGLGGGLPIGAFLATGPAAELLTLGLHGSTFGGNPVCTAAALAVLRVLATQGLVRRAEVLGDSMRIGIESLSHPLIDQVRGRGLLLGIVLTAPRAKDIEKAARDAGFLVNATAPEVIRLAPPLIITESQIDSFITALPGILDASIAELGKKA
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