Gene ML1417 in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namecdh
Gene length807 bp
IdentifierML1417
Location 1699652 bp
Protein summary information
Molecular mass29463.3 Da
Isoelectric point5.1
Protein length269 amino acids
Structural information
PFAMPF02611
Orthologs
M. tuberculosis H37RvRv2289
M. lepromatosis Mx1-22AMLPM_1417
Cross-references
UniProtQ9CC08
Gene OntologyIntegral to membrane, Phospholipid biosynthetic process, Plasma membrane, Cdp-diacylglycerol diphosphatase activity
Enzyme Classification3.6.1.26
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
Productpossible CDP-diacylglycerol pyrophosphatase Cdh (CDP-diacylglycerol diphosphatase) (CDP-diacylglycerol phosphatidylhydrolase)
CommentsML1417, len: 268 aa. Possible CDP-diacylglycerol pyrophosphatase. Similar to several CDP-diacylglycerol pyrophosphatases (EC 3.6.1.26) involved in phospholipid biosynthesis, including: CDH_SALTY|P26219 from Salmonella typhimurium (251 aa), Fasta scores: E(): 1.6e-25, (39.1% identity in 220 aa overlap) and Rv2289|CDH_MYCTU|Q50676 from Mycobacterium tuberculosis (260 aa), Fasta scores: E(): 0, (66.4% identity in 256 aa overlap).
Functional categoryLipid metabolism
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS16996521700458+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML1417|cdh
LRRSIILVSVSVAIAMLTGASIAEAEPMPPNNPSAATRDALWKIVHDRCELGYQHTGAYAPCTLVDEQAGTALFKANYDPNQYLLLPLARVTGIEDPALQELASPNYLYNAWAARGFVSSRLNNSLPEPDIFLAINPKNARTQDQLHIHISCVSPTTAEILKQVNWAEYVGWKPLPVTLQDHTYQALAVNRSTFESKSLFRDIQTKVTADGNTMDHASVAVANIAPDQFLLLVAEGTEDQAIAAEELQDHNCSIAKRLTGQLDMETRR
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