Gene ML1424c in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameML1424c
Gene length1071 bp
IdentifierML1424c
Location 1711570 bp
Protein summary information
Molecular mass39154.8 Da
Isoelectric point5.89
Protein length357 amino acids
Structural information
PFAMPF00005, PF08402
Orthologs
M. tuberculosis H37RvRv2038c
M. lepromatosis Mx1-22AMLPM_1424
Cross-references
UniProtQ7AQ54
Gene OntologyAtp-binding cassette (abc) transporter complex, Atpase activity, Carbohydrate transport, Hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances, Sugar:hydrogen symporter activity, Atp binding
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductProbable sugar-transport ATP-binding protein ABC transporter
CommentsML1424c, len: 356 aa. Probable sugar-transport ATP-binding protein ABC transporter. Highly similar to several binding-protein-dependent transport proteins including: Escherichia coli SN-glycerol-3-phosphate transport ATP-binding protein SW:UGPC_ECOLI (P10907) (356 aa), Fasta scores: E(): 0, 47.9% identity in 363 aa overlap and Mycobacterium tuberculosis ABC-type sugar transport protein Rv2038c TR:O53482 (EMBL:AL021899) (357 aa), Fasta scores: E(): 0, 79.7% identity in 355 aa overlap. Also similar to ML1089, ML0669 and ML1892 from M. leprae. Contains Pfam match to entry PF00005 ABC_tran, ABC transporter. Contains PS00017 ATP/GTP-binding site motif A (P-loop). Contains PS00211 ABC transporters family signature.
Functional categoryCell wall and cell processes
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS17115701712640-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML1424c|ML1424c
MASVTFEQATRQFPDTDRPALDRLDLDVDDGEFVVVVGPSGCGKTTSLRMVAGLETLDSGCIRIGDRDVTHVDPKDRDVAMVFQNYALYPHMTVAQNLGFALKISKISKAEIHDRILVVAKLLDLQPYLDRKPKDLSGGQRQRVAMGRAIVRRPQVFLMDEPLSNLDAKLRAQTRNQIAELQCQLGTTTVYVTHDQVEAMTMGDRVAVLCYGVLQQFATPRELYHKPENVFVAGFIGSPGMNLVTLSIVDSSVLLGDWPIRIPREIASAASEVIIGVRPEHFELGSLGVEVEIDMVEELGADAYLYGRIAGASKVTDQLVVARVDGRNPPAKGSRVRLYTEPGNVHFFGVDGHRIS
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