Gene ML1440c in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameppm1a
Gene length834 bp
IdentifierML1440c
Location 1733643 bp
Protein summary information
Molecular mass30141.0 Da
Isoelectric point7.2
Protein length278 amino acids
Structural information
PFAMPF00535
Orthologues
M. tuberculosisRv2051c
Cross-references
UniProtQ7AQ50
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductPolyprenol-monophosphomannose synthase Ppm1a
CommentsML1440c, len: 277 aa. Probable ppm1a, Polyprenol-monophosphomannose synthase. Highly similar to C-terminus of a Polyprenol-monophosphomannose synthase from Mycobacterium tuberculosis Rv2051c TR:O53493 (EMBL:AL021899) (874 aa), Fasta scores: E(): 0, 78.9% identity in 275 aa overlap. Homology to Rv2051c continues downstream of this ORF in a different frame suggesting a possible frameshift. Also similar to other glycosyl transferases e.g. Q827K1 Putative glycosyl transferase from Streptomyces avermitilis (265 aa), fasta scores: E(): 1.3e-57, (56.274% identity in 263 aa overlap). Contains Pfam match to entry PF00535 Glycos_transf_2, Glycosyl transferases.
Functional categoryCell wall and cell processes
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS17336431734476-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML1440c|ppm1a
MITGQPARKISGNRPSQCVLVIIPTFNELENLPVTHGRLKDAYPEIHVLIVDDGSPDGTGELADELAQVDPGCTHVMHRTTKDGLGTAYLAGFAWGMSRDYSVLVEMDADGSHAPEQLHRLLGAVDAGADLAIGSRYVNGGTVRNWPWQRLALSKTANKYSRLALGIDVHDITAGYRAYRREVLEAIDLDSVASKGYCFQIDLTWRTVNNGFVIIEVPITFTEREFGLSKMSGSNIREALVKVTRWGIDGRIQRARTGRAYNSVSRGGGTGSSPSAP
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