Gene ML1444 in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameML1444
Gene length699 bp
IdentifierML1444
Location 1738599 bp
Protein summary information
Molecular mass25219.9 Da
Isoelectric point9.42
Protein length233 amino acids
Structural information
PFAMPF01738
Orthologs
M. tuberculosis H37RvRv2054
M. lepromatosis Mx1-22AMLPM_1444
Cross-references
UniProtQ9CC04
Gene OntologyHydrolase activity
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductCONSERVED HYPOTHETICAL PROTEIN
CommentsML1444, len: 232 aa. Conserved hypothetical protein. Highly similar to Mycobacterium tuberculosis Rv2054 TR:O86353 (EMBL:AL021899) Conserved hypothetical protein (237 aa), Fasta scores: E(): 0, 76.1% identity in 230 aa overlap. Weakly similar to several carboxymethylenebutenolidases (EC 3.1.1.45) involved in 3-chlorocatechol degradation e.g. Pseudomonas putida SW:CLCD_PSEPU (P11453) (236 aa), Fasta scores: E(): 7.6e-06, 28.6% identity in 234 aa overlap. Contains Pfam match to entry PF01738 DLH, Dienelactone hydrolase family.
Functional categoryConserved hypotheticals
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS17385991739297+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML1444|ML1444
MTKIQIDAPDGPIDALLSVPPGPEPWPGVVVIHDAIGYEPDKESTNNHIAMAGYVAITPNLYSRGSRARCITRVMRELLTKRGRAFDDILATRDYLLAMPKCSGRVGIAGFCMGGRFALVMSPKGFDASAPFYGTPLPRNLSETLNGACPIVASFGGRDPLGIGAPKRLRQATQTRHITTDIKVYPDAGHSFANKLPGQPLMRITGFGYNQAATEDAWSRVFAFFDKHLRTD
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