Gene ML1452c in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameML1452c
Gene length675 bp
IdentifierML1452c
Location 1746891 bp
Protein summary information
Molecular mass24545.6 Da
Isoelectric point5.3
Protein length225 amino acids
Structural information
PFAMPF00300
Orthologs
M. tuberculosis H37RvRv2419c
M. lepromatosis Mx1-22AMLPM_1452
Cross-references
UniProtQ9CC00
Gene OntologyMetabolic process, Catalytic activity
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE PHOSPHOGLYCERATE MUTASE (PHOSPHOGLYCEROMUTASE)
CommentsML1452c, len: 224 aa. Probable phosphoglycerate mutase (EC 5.4.2.1). Similar to several including: Mycobacterium tuberculosis Rv2419c TR:P71724 (EMBL:Z81368) (223 aa), Fasta scores: E(): 0, 80.4% identity in 224 aa overlap. Contains Pfam match to entry PF00300 PGAM, Phosphoglycerate mutase family. Contains PS00175 Phosphoglycerate mutase family phosphohistidine signature. BELONGS TO THE PHOSPHOGLYCERATE MUTASE FAMILY.
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS17468911747565-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML1452c|ML1452c
MRTRRLVMLRHGQTDFNLGGRMQGQLDTELSELGRAQAVAVAEVLGKLQPLRIVSSDLRRAYDTAIKLGERTGLKIWVDDRLREAHLGDWQGLTHSQIDADAPGARLAWREDATWAPHSGESRVDVAARSLPVVTEVVSGAPEWGDCHEPDRPVVLVAHGGLITALSAALLRLPVANWSILGSMGNASWVQLSGHSDESDSELDLIQWRLDVWNASVQVSNDVL
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