Gene ML1468c in Mycobacterium leprae TN
Go to browser
virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namerne
Gene length2775 bp
IdentifierML1468c
Location 1765045 bp
Protein summary information
Molecular mass101226.0 Da
Isoelectric point4.52
Protein length925 amino acids
Structural information
PFAMPF00575, PF10150
Orthologs
M. tuberculosis H37RvRv2444c
M. lepromatosis Mx1-22AMLPM_1468
Cross-references
UniProtQ9CBZ1
Gene OntologyRna processing, Cytoplasm, Ribonuclease activity, Rna binding
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
Productpossible ribonuclease E Rne
CommentsML1468c, len: 924 aa. Possible rne, ribonuclease (EC 3.1.-.-). Highly similar in parts to many ribonucleases e.g. Escherichia coli ribonuclease E SW:RNE_ECOLI (P21513) (1061 aa), Fasta scores: E(): 1.6e-22, 36.4% identity in 429 aa overlap and Mycobacterium tuberculosis Rv2444c TR:P71905 (EMBL:Z81451) (953 aa), Fasta scores: E(): 0, 74.2% identity in 966 aa overlap. Contains Pfam match to entry PF00575 S1, S1 RNA binding domain.
Functional categoryInformation pathways
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS17650451767819-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML1468c|rne
VIDGAPPLEPSKEPTQHMELPDRLRVHSLARTLGTTSRRVLDVLSALDGRIRSAHSSVDRVDAVRVRDLLASQPNSPHELTAVPDNPVALEERDSRLVLETTVERPHYMPLFVAPQPIEVDDDSCADDDVESGDDSDVGDDEEQPDRPANRRRRRGRRGRGRGRGEQGGSDVQSDDVDGAVDSTESEDFDGQDFDESEDTEIGYDESGSSEAGNRRRRRRRRRKSGVGEDEGCAPDDPPNTVVHERTPRAAGRSASFDNGVNGTGSADIKGIDGSTRLEAKRQRRRDGRDAGRRRSSVLSEAEFLARRESVERVMVVRDRIRTEPPHPGARYTQIAVLEDGIVVEHFVTSAASASLVGNIYLGIVQNVLPSMEAAFVDIGRGRNGVLYAGEVNWEAAGLGGADRKIEQALKPGDYIVVQVNKDPVGHKGARLTTQVSLAGRYLVYVPGASSTGISRKLPDTERQRLKEILREVVPPDAGVIIRTASEGVKEEDIRKDVTRLQEHWEQIEAKTIQTKEKAAGAAVALYEEPDVLVKVIRDLFNDDFSGLVVSGDEAWNTINEYVNSVAPELVSKLTKYDPPIGPDGQHGPDVFAVHRIDEQLAKAMDRKVWLPSGGTLVIDRTEAMTVIDVNTGKFTGSGGNLEQTVTKNNLEAAEEIVRQLRLRDIGGIVVIDFIDMVLESNRDLVLRRLTEVLARDRTRHQVSEVTSLGLVQLTRKRLGTGLVEAFSTSCPNCTGRGILLHTDPANSTPMVGRKSESGGRRSKRSKKNRSDETAVVKVPVHAPGEHPMFKAMAAGSSSVVVGGEDESNESGTELTGKIDEPLEEQAVAGLDDVDQEDFDTDEEDDLDDDEELDDEEDLGDDDEELDLDDDLDVDEDESDSEADLDSADVLDRSTLLIRNRSGFARPRRRRAAGRPAGPPIHVD
Bibliography
No article yet recorded