Gene ML1469c in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namendk
Gene length411 bp
IdentifierML1469c
Location 1768162 bp
Protein summary information
Molecular mass14643.7 Da
Isoelectric point4.95
Protein length137 amino acids
Structural information
PFAMPF00334
Orthologs
M. tuberculosis H37RvRv2445c
M. lepromatosis Mx1-22AMLPM_1469
Cross-references
UniProtQ9CBZ0
Gene OntologyCtp biosynthetic process, Gtp biosynthetic process, Utp biosynthetic process, Cytoplasm, Magnesium ion binding, Nucleoside diphosphate kinase activity, Atp binding
Enzyme Classification2.7.4.6
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE NUCLEOSIDE DIPHOSPHATE KINASE NDK (NDK) (NDP KINASE) (NUCLEOSIDE-2-P KINASE)
CommentsML1469c, len: 136 aa. Probable nucleoside diphosphate kinases (EC 2.7.4.6). Highly similar to many nucleoside diphosphate kinases including: Bacillus subtilis SW:NDK_BACSU (P31103) (149 aa), Fasta scores: E(): 5e-27, 55.7% identity in 131 aa overlap and Mycobacterium tuberculosis Rv2445c SW:NDK_MYCTU (P71904) (136 aa), Fasta scores: E(): 0, 87.4% identity in 135 aa overlap. Contains Pfam match to entry PF00334 NDK, Nucleoside diphosphate kinases.
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS17681621768572-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML1469c|ndk
VTERTLVLIKPDAVERQLIGEIISRIERKGLTIAALELRQVGEELASQHYAEHESKPFFGSLLEFITSGPVMAAIVEGPRAVAAVRQLTGGTDPVEKAAPGTIRGDLALETQFNLVHGSDSTASAQREIALWFPGI
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