Gene ML1498c in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nametypA
Gene length1887 bp
IdentifierML1498c
Location 1805545 bp
Protein summary information
Molecular mass67962.4 Da
Isoelectric point5.06
Protein length629 amino acids
Structural information
PFAMPF00009, PF00679, PF03144
Orthologs
M. tuberculosis H37RvRv1165
M. lepromatosis Mx1-22AMLPM_1498
Cross-references
UniProtQ9CBX2
Gene OntologyGtpase activity, Intracellular, Translation elongation factor activity, Gtp binding
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductPOSSIBLE GTP-BINDING TRANSLATION ELONGATION FACTOR TYPA (TYROSINE PHOSPHORYLATED PROTEIN A) (GTP-BINDING PROTEIN)
CommentsML1498c, len: 628 aa. Possible typA, GTP-binding, protein elongation factor. Highly similar to several GTP-binding proteins including: Escherichia coli SW:TYPA_ECOLI (P32132) (591 aa), Fasta scores: E(): 0, 46.1% identity in 610 aa overlap which belongs to the GTP-binding elongation factor family and Mycobacterium tuberculosis hypothetical protein Rv1165 TR:O06563 (EMBL:Z95584) (628 aa), Fasta scores: E(): 0, 85.2% identity in 628 aa overlap. Contains Pfam match to entry PF00009 GTP_EFTU, Elongation factor Tu family. Contains PS00301 GTP-binding elongation factors signature. Contains PS00017 ATP/GTP-binding site motif A (P-loop).
Functional categoryInformation pathways
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS18055451807431-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML1498c|typA
VPFRNVAIVAHVDHGKTTLVDAMLRQSGALHERGQVQERVMDTGDLEREKGITILAKNTAVHCHNSDGTVTVINVIDTPGHADFGGEVERGLSMVDGVLLLVDASEGPLPQTRFVLRKTLAAHLPVILVVNKTDRPDARIAEVVEASHDLLLDVASDLDEEAAAAAERALGLPTLYASGRAGIASTEQPADGAVPTGDNLDPLFDVLMEHIPSPKGDPEAPLQALVTNLDASAFLGRLALVRIYNGKLRKGQQVAWMREVDGLPVTTDAKITELLVTKGVERSTTEEATAGDIVAVAGLPEIMIGDTLADPEHAHALPRITVDEPAISVTIGTNTSPLAGKVSGHKLTARMVRGRLDAELVGNISIRVVDIGRPDAWEVQGRGELALAVLVETMRREGFELTVGKPQVVTRTIDGKLHEPFEVMTIDCPEEFVGAITQLMAGRKGRMEEMANHAVGWVRMDFIVPSRGLIGFRTDFLTLTRGTGIANAVFDSYRPWAGEIRARDTGSLVSDRPGTITPFALLQLADRGQFFVSPGQDTYQGMVVGINPRPEDLDINVTREKKLTNMRSSTANVIETLTKPLELDLERAMEFCSFDECVEVTPEIVRVRKIELESNARARGRARAKVRG
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