Gene ML1512c in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameML1512c
Gene length1677 bp
IdentifierML1512c
Location 1822935 bp
Protein summary information
Molecular mass59315.2 Da
Isoelectric point5.85
Protein length559 amino acids
Structural information
PFAMPF00753, PF07521
Orthologs
M. tuberculosis H37RvRv2752c
M. lepromatosis Mx1-22AMLPM_1512
Cross-references
UniProtQ9CBW5
Gene OntologyHydrolase activity
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
Productconserved hypothetical protein
CommentsML1512c, len: 558 aa. Conserved hypothetical protein. Highly similar to many proteins of undefined function including: Bacillus subtilis SW:YKQC_BACSU (Q45493) (555 aa), Fasta scores: E(): 0, 36.9% identity in 547 aa overlap and Mycobacterium tuberculosis Rv2752c TR:O33294 (EMBL:AL008967) (558 aa), Fasta scores: E(): 0, 89.1% identity in 558 aa overlap. Contains Pfam match to entry PF02147 UPF0036, Uncharacterized protein family UPF0036. Contains Pfam match to entry PF00753 lactamase_B, Metallo-beta-lactamase superfamily.
Functional categoryConserved hypotheticals
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS18229351824611-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML1512c|ML1512c
VDVALAPPGPLASGGLRVTALGGISEIGRNMTIFEHLGRLLIIDCGVLFPGHDEPGVDLILPDLRHIEDRLDDIEALVLTHAHEDHIGAIPFLLKLRSDIPVVGSKFTLALVAAKCREHRIKPVFVEVVGGQSSRHGVFECEYFAVNHSIPDALTIAVYTGAGTVLHTGDIKLDQLPLDGRPTDLPGMSRLGDAGVDLFLCDSTNAEIPGVGPSESEVGPTLHRLIQGADGRVIVACFASNVDRVQQVIDAAVALGRRVSFVGRSMVRNMSIARDLGFLRVDDSHMIDIAAAEMMAPEQVVLITTGTQGEPMSALSRMSRGEHQSITLTSGDLVVLSSSLIPGNEEAVYGVIDALAKIGARVVTNAQARVHVSGHAYAGELLFLYNGVRPRQVMPVHGTWRMLRANAKLAASTGVPEDSILIAENGVSVDLVAGKASVSGAVPVGKMFVDGLITGDVGDVILGERLILSSGFVAVTVVVKRSTGRPVTVPQLYSRGFSEDPKALEPAVRKVEAELESLLAENVTDPSKIAQAVRRAIGKWVGETYRRQPMIVPTVIEV
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