Gene ML1536c in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameeccA5
Gene length1833 bp
IdentifierML1536c
Location 1851736 bp
Protein summary information
Molecular mass67767.9 Da
Isoelectric point5.76
Protein length611 amino acids
Structural information
PFAMPF00004
Orthologs
M. tuberculosis H37RvRv1798
M. lepromatosis Mx1-22AMLPM_1536
Cross-references
UniProtQ9CBV5
Gene OntologyNucleoside-triphosphatase activity, Atp binding
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductESX CONSERVED COMPONENT ECCA5
CommentsML1536c, len: 610 aa. esx conserved component, highly similar to several Mycobacterium tuberculosis proteins of undefined function e.g. Rv1798|YH98_MYCTU (O53947) (610 aa), Fasta scores: E(): 0, 89.7% identity in 609 aa overlap. The C-terminus of this protein is also similar to several including: Bacillus subtilis stage V sporulation protein K SP5K_BACSU (P27643) (322 aa), Fasta scores: E(): 2.2e-20, 34.5% identity in 310 aa overlap. Contains PS00017 ATP/GTP-binding site motif A (P-loop).
Functional categoryCell wall and cell processes
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS18517361853568-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML1536c|eccA5
MTRPQSTAEDARNAMVAGLLASGISVNGLQPSHNPQVASQMFRTATTLDPGMCDAWQARILAGDQSIEVLAGAWSSIRTFGWETRRLGVTDLQFRPEVSDGLFLRLAVTSVESLACAYAAVLVKAKRYAEAAKLLESVEPRHPFDTELVNYVRGMLYFRTKRWPDVLTQFPEGKQWRHPDLKAAGAAMATSALASLGVFEEAFRRGKEAIEGDRVPRAANIALYTQGMCLRHVGREDEAVELLRRVYSRDAKFTPAREALDNNNFRLTLTDPETIEARTDPWDPDSAPTRAQTEAARYARIAAKYLAEGDAELNAMLGMEQAKREIKLIKSTTRVNLARAKMGLPVPVTSRHTLLLGPPGTGKTSVARAFTKQLCGLTVLRKPLVVETSRTKLLGRHMADAEKNTEEMLEGALGGAVFFDEMHTLHEKGYTRGDPYGNAIINTLLLYMENHRDELVVFGAGYAKAMDKMLEVNQGLRRRFSTVIEFFSYTPEELIALTQLMGQENEDVITEQEAQVLLPSYTKFYLDETYSEDGDLIRGIDMLGNAGFVRNVVEKARDHRSFRLDDEDLDAVLASDLTQFSAEQLLRFKELTSADLTEGLSAAVAERKSS
Bibliography