Gene ML1538c
in Mycobacterium leprae TN
General annotation
| Type | CDS |
| Function | Unknown |
| Product | PROBABLE PROLINE RICH MEMBRANE-ANCHORED MYCOSIN MYCP5 (SERINE PROTEASE) (SUBTILISIN-LIKE PROTEASE) (SUBTILASE-LIKE) (MYCOSIN-5) |
| Comments | ML1538c, len: 567 aa. Probable mycP5, proline rich membrane-anchored mycosin. Highly similar to several from Mycobacterium tuberculosis including: O53945|Rv1796 mycP5, proline rich membrane-anchored mycosin (585 aa), fasta scores: E(): 2e-134, (73.077% identity in 572 aa overlap); and Rv0291 TR:O53695 (EMBL:AL021930) mycP3, membrane-anchored serine protease (461 aa), Fasta scores: E(): 0, 37.6% identity in 572 aa overlap. Also similar to ML2528 and ML0041 from M. leprae. Contains possible membrane spanning hydrophobic domain. Contains 2 Pfam matches to entry PF00082 Peptidase_S8, Subtilase family. Contains PS00136 Serine proteases. Contains PS00137 Serine proteases. |
| Functional category | Intermediary metabolism and respiration |
| Mutant | Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 1854791 | 1856494 | - |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium leprae TN|ML1538c|mycP5
VFVALALLTSGAFAGLPPAYAISPPKIDPGAVPPDGPPGPATPMKQYSYCTEVGVLPETDFRLLPKYMDMLNMFDAWEFGRGGGQKIAVIDTGVTPHPRLPHLIAGGDYVMAGGDGLSDCDAHGTIVASMIGAAPATGAPVPAAPRKPVPIPTTEKSPPPQTVTLSPLPQTVTVIPVPPPPEEGLSPPGVPPPLQSGQHASSGRWDGSTVTISNYLGGRQVIAIDNPANSSPRAPVPNQPSSPLAPTSRPDAYAGIASDVDILSIRQSSQAFGFKDLYTGDADPQTSQTIHYIQTMARAIVHAANMGATVINISEVTCMSARNVIDQRALGAAVRYAAVDKNVVIVAAAGDSSKKNCKQNPLFDPLQPNDPRGWNGVNTVVTPSWFSEYVLTVGAVDSHGQPLTQTSIAGPWVSIAAPGTDIIGLSPRDDSLINAIDGPDNTLLVPTGTSFSAAIVSGVAALVRGRYPQLTAYQVINRLIHTARSPARGVDNQVGYGIVDPLAALTWDVPEGPAKPPPQLSSPLNLPKLPAHRDMVPVWVAAGGLTTAVLIGAAAFGTAMLVRRTQK
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