Gene ML1544c in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameeccB5
Gene length1521 bp
IdentifierML1544c
Location 1866375 bp
Protein summary information
Molecular mass53849.1 Da
Isoelectric point7.05
Protein length507 amino acids
Structural information
PFAMPF05108
Orthologs
M. tuberculosis H37RvRv1782
M. lepromatosis Mx1-22AMLPM_1544
Cross-references
UniProtQ7AQ46
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductESX CONSERVED COMPONENT ECCB5. POSSIBLE MEMBRANE PROTEIN.
CommentsML1544c, len: 506 aa. esx conserved component, probable membrane protein. Highly similar to many Mycobacterium tuberculosis proteins of unknown function including:Rv1782 TR:O53933 (EMBL:AL022021) (506 aa), Fasta scores: E(): 0, 82.6% identity in 506 aa overlap. Also similar to ML0054 from M. leprae. Contains a possible membrane spanning hydrophobic domain.
Functional categoryCell wall and cell processes
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS18663751867895-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML1544c|eccB5
VAEESSGRRGSEYGLGLSTRTQVTGYQFLARRTAMALTRWRVRMEVEPGRRQTLAVVASVSAALLGCLGALLWSFISPSGQLNESPIIIDRDSGALYVRVGDRLYPALNLASARLITGRPDNPHAVRSSQIATLPHGPLVGIPGAPSELSPETPQTSSWLVCDTVATSTGIGSSSGVTVTVIDGSPDLSGHRRVLTGSDAVVLHYGGDAWVIRQGRRSRIDAMNRSVLLPLGLTPEQVSQARPMSRALFDALPVGPDLVVPDVPNEGNPASFPGAPGPVGTVIVTPQISGPQQYSLVLADGVETVSPLVAQIMQNAGKPGNTKLITVAPSVLVKMPVVNKLDLSVYPDTPLQVVDLRENPSTCWWWERTAGESRSRIQVITGSTIPINSADVKKVVSLVKADTTGREADQVYFGSNYANFVAVTGNNPAAQTTESLWWVTRTGARFGVEDTKDVRDALGLNGTPNLAPWVALRLLSQGPTLSRADALMEHDTLPMDMTPAELVVPK
Bibliography