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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
General annotation
TypeCDS
FunctionUnknown
ProductPOSSIBLE INTEGRAL MEMBRANE EFFLUX PROTEIN EFPA
CommentsML1562c, len: 534 aa. Possible efpA, integral membrane efflux protein. Highly similar to several transmembrane transport proteins including: Streptomyces lipmanii SW:PUR8_STRLP (P42670) (503 aa), Fasta scores: E(): 0, 33.3% identity in 481 aa overlap and Mycobacterium tuberculosis Rv2846c TR:O05813 (EMBL:Z95207) (530 aa), Fasta scores: E(): 0, 86.5% identity in 535 aa overlap. Contains multiple possible membrane spanning hydrophobic domains. Contains Pfam match to entry PF00083 sugar_tr, Sugar (and other) transporter.
Functional categoryCell wall and cell processes
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS18863001887904-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
       
Protein sequence
>Mycobacterium leprae TN|ML1562c|efpA
MVTLYDHERAVHNWTAARSDRPAPSRLTQQVEPASERTSKYPTLLPSGRFPSGRFIAAVIVIGGMQLLATMDSTVAIVALPKIQNELSLSDAGRSWGITAYVLTFGGLMLLGGRLGDTIGRKRTFIVGVALFTISSVLCAVAWDEVTLVIARLLQGIGSAIASPTGLALVATTFSKGSARNTATAVFAAMTAIGSVMGLVVGGALTEVSWRLAFLVNVPIGLVMIYLARTALHETHKERMKLDAAGAILATLACTAAVFAFSMGPEKGWISLTTIGSGLVALVAAIAFAVVERTAENPVVPFDLFRDRNRLVTFIAIFLAGGVIFSLTVSIGLYIQDILGYSALRAGIGFIPFVIAMGIGLGVSSQLVSRFSPRVLTIGGGWLLMVAMLYGWAFMNRGVPYFPNLLAPIVVGGIGIGMAVVPLTLSAIAGVGFDRIGPVSAIALMLQSLGGPLVLAVIQAVITSRTLYLGGTTGPVKFMNDAQLRALDHGYTYGLLWVAGAVVIVGVAALFIGYTPEQVAYAQEVKEAVDAGEL
      
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