Gene ML1589c
in Mycobacterium leprae TN
General annotation
Type | CDS |
Function | Unknown |
Product | PROBABLE INTEGRAL MEMBRANE PHOSPHATIDATE CYTIDYLYLTRANSFERASE CDSA (CDP-DIGLYCERIDE SYNTHETASE) (CDP-DIGLYCERIDE PYROPHOSPHORYLASE) (CDP-DIACYLGLYCEROL SYNTHASE) (CDS) (CTP:PHOSPHATIDATE CYTIDYLYLTRANSFERASE) (CDP-DAG SYNTHASE) (CDP-DG SYNTHETASE) |
Comments | ML1589c, len: 312 aa. Probable cdsA, integral membrane phosphatidate cytidylyltransferase (EC 2.7.7.41). Highly similar to several e.g. Mycobacterium tuberculosis Rv2881c SW:CDSA_MYCTU (Q10807) (306 aa), Fasta scores: E(): 0, 70.3% identity in 313 aa overlap and Q8FP76 Putative phosphatidate cytidylyltrans from Corynebacterium efficiens (297 aa), fasta score: E(): 6.2e-54, (48.986% identity in 296 aa overlap). Contains multiple possible membrane spanning hydrophobic domains. Contains Pfam match to entry PF01148 Cytidylyltrans, Phosphatidate cytidylyltransferase. Contains PS01315 Phosphatidate cytidylyltransferase signature. Contains PS00017 ATP/GTP-binding site motif A (P-loop). |
Functional category | Lipid metabolism |
Mutant | Check for mutants available at TARGET website |
Coordinates
Type | Start | End | Orientation |
---|---|---|---|
CDS | 1913904 | 1914842 | - |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium leprae TN|ML1589c|cdsA VASTDPGTGTPLDESVPGIKRAMRQSTKNTPRAGRNLPAAIAVGLSIGGVLVATLVFAPRIWVVLCAGAIFVASHEVVRRLREAGYVIPAIPLLIGGQFTVWLTWPYRTVGALAGFGATVVVCMIWRLVMHDNSKQHESREALAGPPVSNYLRDASATVFLAAWVPLFASFAALLVYPKDGAGRVFCLMIAVVASDVGGYTVGVLFGKHPLVPRISPNKSWEGFAGSLVCGTTATILTATFLAGKTPWVGALLSFVLVLTCTLGDLVESQVKRDLGIKDMGRLLPGHGGLMDRLDGVLPSAVVAWTMLTLLP
Bibliography
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