Gene ML1622c in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameffh
Gene length1566 bp
IdentifierML1622c
Location 1943808 bp
Protein summary information
Molecular mass55079.5 Da
Isoelectric point9.07
Protein length522 amino acids
Structural information
PFAMPF00448, PF02881, PF02978
Orthologs
M. tuberculosis H37RvRv2916c
M. lepromatosis Mx1-22AMLPM_1622
Cross-references
UniProtO33013
Gene OntologyGtp binding, Srp-dependent cotranslational protein targeting to membrane, Nucleoside-triphosphatase activity, Signal recognition particle, endoplasmic reticulum targeting, 7s rna binding
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE SIGNAL RECOGNITION PARTICLE PROTEIN FFH (FIFTY-FOUR HOMOLOG) (SRP PROTEIN)
CommentsML1622c, len: 521 aa. Probable ffh, signal recognition particle protein. Highly similar to many signal recognition particle proteins, involved in the reconition of the signal sequence and the efficient export of the protein, including: Bacillus subtilis SW:SR54_BACSU (P37105) (446 aa), Fasta scores: E(): 0, 51.0% identity in 435 aa overlap and Mycobacterium tuberculosis Rv2916c SW:SR54_MYCTU (Q10963) (525 aa), Fasta scores: E(): 0, 87.8% identity in 526 aa overlap. Contains Pfam match to entry PF00448 SRP54, SRP54-type protein. Contains PS00017 ATP/GTP-binding site motif A (P-loop).
Functional categoryCell wall and cell processes
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS19438081945373-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML1622c|ffh
VFESLSNRLTGVIQGLRGKGRLTDADIEATTREIRLALFEADVSLPVVRAFVHRIKERARGTEVSAALNPAQQIVKIVNEELIGILGGETRQLAFAKTPPTVVMLAGLQGSGKTTLAGKLAVRLRRQGHTPLLVACDLQRPAAVNQLQVVGERAGVPVFAPHPGASPDSGPGDPVAVASAGLVEARAKHFDVVIVDTAGRLGIDDELMAQAGAIREAINPDEVLFVLDAMIGQDAVTTAAAFGAGVGFTGVVLTKLDGDARGGAALSVREVTGVPILFATTGEKLDDFDVFHPDRMASRILGMGDVLSLIEQAEQVFDAEQAEAAAAKIVAGELTLEDFLEQMLAVRKMGLIGNLLGMLPGAGQVKEVLEQVDDKQLDRLQAIIRGMTPQERADPKIINASRRLRIANGSGVTVSEVNQLVDRFFEARKMMSSVLGGMGIPGMGRKSATRKSKGGKGKKRARGPTSPKVRSPFGPARPGMPDMMNMPPSFPDLSQMPDGLNELPPGLAAFDLSKLKFPGKT
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