Gene ML1631c in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameglnA2
Gene length1347 bp
IdentifierML1631c
Location 1962937 bp
Protein summary information
Molecular mass49760.9 Da
Isoelectric point5.03
Protein length449 amino acids
Structural information
PFAMPF00120, PF03951
Orthologs
M. tuberculosis H37RvRv2222c
M. lepromatosis Mx1-22AMLPM_1631
Cross-references
UniProtQ9CBT3
Gene OntologyGlutamine biosynthetic process, Glutamate-ammonia ligase activity
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE GLUTAMINE SYNTHETASE GLNA2 (GLUTAMINE SYNTHASE) (GS-II)
CommentsML1631c, len: 448 aa. Probable glnA2, glutamine synthase class II (EC 6.3.1.2). Highly similar to many glutamine synthetases including: Bacillus subtilis SW:GLNA_BACSU (P12425) (443 aa), Fasta scores: E(): 0, 45.4% identity in 445 aa overlap and Mycobacterium tuberculosis Rv2222c SW:GLN2_MYCTU (Q10378) (446 aa), Fasta scores: E(): 0, 93.3% identity in 448 aa overlap. Also similar to ML0925 from M. leprae. Contains Pfam match to entry PF00120 gln-synt, Glutamine synthetase.
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS19629371964283-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML1631c|glnA2
MDRQKEFVLRTLEERDIRFVRLWFTDVLGYLKSVAIAPAELEGAFEEGIGFDGSSIEGFARVSESDTVAHPDPSTFQILPWATTAGHHHSARMFCDITMPDGSSSWADPRHVLRRQLTKANDLGFSCYVHPEIEFFLLKAGPEDGSMPIPVPVDNAGYFDQAVHDSALNFRRHAIEALEFMGISVEFSHHEGAPGQQEIDLRFADALSMADNVMTFRYVIKEVAIENGARASFMPKPFAQHPGSAMHTHMSLFEGDVNAFHSDDDPLQLSDVGKSFIAGILEHASEISAVTNQWVNSYKRLVVGGEAPTTASWGAANRSALVRVPMYTPHKTSSRRVEVRSPDSACNPYLAFAVLLAAGLRGVEKGYVLGPQAEDNVWDLTPEERLAMGYRELPTSLDSALGAMEVSEFVAEALGEHVFDFFLRNKRAEWANYRSHVSLYELKTYLSL
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