Gene ML1632c in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameML1632c
Gene length1536 bp
IdentifierML1632c
Location 1964380 bp
Protein summary information
Molecular mass54560.1 Da
Isoelectric point4.58
Protein length512 amino acids
Structural information
PFAMPF00561
Orthologs
M. tuberculosis H37RvRv2223c
M. lepromatosis Mx1-22AMLPM_1632
Cross-references
UniProtQ9CBT2
Gene OntologyHydrolase activity
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductProbable exported protease
CommentsML1632c, len: 511 aa. Probable exported protease. Highly similar to Mycobacterium tuberculosis Rv2223C SW:YM23_MYCTU (Q10508) (520 aa), Fasta scores: E(): 0, 75.8% identity in 520 aa overlap. And similar to Streptomyces lividans tripeptidylaminopeptidase precursor TR:Q54410 (EMBL:L27466) (537 aa), Fasta scores: E(): 0, 30.9% identity in 489 aa overlap. Also similar to ML1633 from M. leprae. Contains Pfam match to entry PF00561 abhydrolase, alpha/beta hydrolase fold.
Functional categoryCell wall and cell processes
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS19643801965915-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML1632c|ML1632c
MVAMPSLRSLSSALLSLGLLLQPAMTPPVVGASPEQTPSPVPEQNWGNCSVFLSDTSDIPSARCATVSVPVDYNNPDGVHAELAVIRAPATGQRIGSLLFNPGGPGASAVDMVAEMIPGLQRTDIGRHFDLVGFDPRGVGHSTPALRCRTDVEFDAYRTEPMVDYSPAGVAHIEQVYKQLAQQCVARVGTAFLANVGTASAARDMDIVRLALGDEQINYLGYSYGTELGTAYLERFSDHVRAMVLDGAIDPSVSSIQKDIQQMAGFQIAFTDYAADCARSASCPLGTDPSQWVNRYHALIDPLVTKPGRTSDPRGLGYADATTGTINALYTPVHWKYLTSGLLGLQRGTDAGDLLLLADDYNGRDRNGHYTNDQDAFNAIRCVDAPVPTDSASWVSADQQIRQAAPFLNYGQFTGNAPRDICALWPVPATSMPHPAPPVAPGKVVVVSTTHDPATPYQAGVDLARELSSPLITYDGTQHTAVFNGDQCVDSAVVHYFVDETLLPASLQCQP
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