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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
General annotation
TypeCDS
FunctionUnknown
ProductProbable exported protease
CommentsML1633c, len: 535 aa. Probable exported protease (EC 3.4.-.-). Highly similar to Q10509|YM24_MYCTU Hypothetical protein Rv2224c from M. tuberculosis (520 aa), fasta scores: E(): 8.6e-188, (84.808% identity in 520 aa overlap) and Mycobacterium tuberculosis Rv2223c SW:YM23_MYCTU (Q10508) (520 aa), Fasta scores: E(): 0, 50.1% identity in 511 aa overlap. Also similar to Streptomyces lividans tripeptidylaminopeptidase precursor TR:Q54410 (EMBL:L27466) (537 aa), Fasta scores: E(): 4.3e-23, 30.7% identity in 508 aa overlap. Note this CDS is also highly similar to the adjoining CDS ML1632. Contains a possible N-terminal signal sequence. Contains Pfam match to entry PF00561 abhydrolase, alpha/beta hydrolase fold.
Functional categoryCell wall and cell processes
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS19659901967597-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
       
Protein sequence
>Mycobacterium leprae TN|ML1633c|ML1633c
VTAAHQEPKPSLAAYVSMALSYRDKIARMLLLGTAIAAVALVLAGCVRVVSGRALMAGPKLGEPVAWAPCRPSNPAVKLPGGALCGKLAVPVDYDHHDDDVAALAMIRFPATGDRMGSLVINPGGPGESGIEAALGVVQTLPKRVRERFDLVGFDPRGVGASRPAVWCNSDADNDRLRSESQVDYSPAGVAHIEDETKQFIGRCIAKMGKIFLENIGTVNVAKDLDAIRAALGDDKLTYLGYSYGTRIGAAYAEAYPQNVRSMILDGAVDPNADPIEADLRQAKGFQDAFNNYAADCARKLSCPLGADPAKAVDVYHNLVNPLVDPNNPMVSRPAPTKDPRGLSYSDAIVGTIMTLYSPTLWHHLTDGLSELVDHRGDTLLALADMYMRRDSQGHYTNATDARVAVNCVDQPPITDRAKVIDEDRRSREVAPFMSYGKFTGDAPLGTCAFWPVPPTSKPHIVSAPGLAPTVVVSTTHDPATPYKAGVDLANQLRGSLLTFDGTQHTVVFQGDSCVDDYVTEYLIGGTTPPSGAKC
      
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