Gene ML1675c in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameung
Gene length684 bp
IdentifierML1675c
Location 2019284 bp
Protein summary information
Molecular mass24655.4 Da
Isoelectric point8.49
Protein length228 amino acids
Structural information
PFAMPF03167
Orthologs
M. tuberculosis H37RvRv2976c
M. lepromatosis Mx1-22AMLPM_1675
Cross-references
UniProtQ9CBS3
Gene OntologyCytoplasm, Uracil dna n-glycosylase activity, Base-excision repair
Enzyme Classification3.2.2.-
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE URACIL-DNA GLYCOSYLASE UNG (UDG)
CommentsML1675c, len: 227 aa. Probable ung, uracil-DNA glycosylase (EC 3.2.2.-). Highly similar to many uracil-DNA glycosylases including: Streptococcus pneumoniae SW:UNG_STRPN (P23379) (123 aa), BlastP Expect 8.6 and Mycobacterium tuberculosis Rv2976c SW:UNG_MYCTU (P95119) (227 aa), Fasta scores: E(): 0, 88.5% identity in 227 aa overlap. Contains Pfam match to entry PF00315 UNG, Uracil-DNA glycosylase. Contains PS00130 Uracil-DNA glycosylase signature.
Functional categoryInformation pathways
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS20192842019967-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML1675c|ung
MTARPLSELVEQGWAAALEPVVDQVAEMGRFLRAEIAAGRRYLPAGHSVLRAFTYPFDNVRVLIVGQDPYPTPGHAVGLSFSVAPDVRPLPRSLANVFDEYTADLGYPLPVCGDLTPWAQRGVLLLNRVLTVRPSNPASHRGKGWEVITECAIRALAARSEPMVAILWGRDAATLKPLLTVDNCVVIESPHPSPLSASRGFFGSRPFSRTNEILVGMGAGPINWRLP
Bibliography
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