Gene ML1679c in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namegpdA2
Gene length1056 bp
IdentifierML1679c
Location 2023092 bp
Protein summary information
Molecular mass35846.3 Da
Isoelectric point6.88
Protein length352 amino acids
Structural information
PFAMPF01210, PF07479
Orthologs
M. tuberculosis H37RvRv2982c
M. lepromatosis Mx1-22AMLPM_1679
Cross-references
UniProtQ9CBR9
Gene OntologyCarbohydrate metabolic process, Glycerol-3-phosphate biosynthetic process, Glycerol-3-phosphate catabolic process, Glycerol-3-phosphate dehydrogenase [nad+] activity, Glycerol-3-phosphate dehydrogenase [nad(p)+] activity, Glycerol-3-phosphate dehydrogenase complex, Oxidation-reduction process, Phospholipid biosynthetic process, Nad binding
Enzyme Classification1.1.1.94
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE GLYCEROL-3-PHOSPHATE DEHYDROGENASE [NAD(P)+] GPDA (NAD(P)H- DEPENDENT GLYCEROL-3-PHOSPHATE DEHYDROGENASE)
CommentsML1679c, len: 351 aa. Probable gpdA, glycerol-3-phosphate dehydrogenase (EC 1.1.1.94). Highly similar to many glycerol-3-phosphate dehydrogenases including: Escherichia coli SW:GPDA_ECOLI (P37606) (339 aa), Fasta scores: E(): 0, 39.9% identity in 341 aa overlap and Mycobacterium tuberculosis Rv2982c TR:P95113 (EMBL:Z83018) (334 aa), Fasta scores: E(): 0, 77.9% identity in 349 aa overlap. Contains Pfam match to entry PF01210 NAD_Gly3P_dh, NAD-dependent glycerol-3-phosphate dehydrogenase.
Functional categoryLipid metabolism
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS20230922024147-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML1679c|gpdA2
VEMAGIVVRSESAVAVMGAGAWGTALAKVLIDAGGPEAGVVLWARRPDVAERINTTRCNRAYLPGTLLPPGIRATADPADALRGASTVLLGVPAQRMRANLERWGGLVADGATLVSLAKGIELGTLMRMSQVIVSVTGVDPAQVAVLSGPNLASEIAQCQPAATVIACSDLGRAVALQRMLSSGYFRPYTNSDVVGTEIGGVCKNVIALACGMAAGVGFGENTAATIITRGLAEIIRLGMALGAQVTTLAGLAGVGDLVATCTSPHSRNRSLGERLGRGEIMQSILHGMDGSDGGDGYVVEGVTSCASVLALASSYDVEMPLTDAVHRVCHKGLSVEKAMALLLGRSTKSE
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