Gene ML1683c
in Mycobacterium leprae TN
General annotation
| Type | CDS |
| Function | Unknown |
| Product | PROBABLE DNA-BINDING PROTEIN HU HOMOLOG HUPB (HISTONE-LIKE PROTEIN) (HLP) (21-KDA LAMININ-2-BINDING PROTEIN) |
| Comments | ML1683c, len: 200 aa. Probable hupB, DNA-binding protein HU homolog. Highly similar to Mycobacterial histone-like proteins e.g. Mycobacterium smegmatis TR:Q9ZHC5 (EMBL:AF068138) (269 aa), BlastP Expect 0.0014 and Mycobacterium tuberculosis Rv2986c SW:DBH_MYCTU (P95109) (214 aa), Fasta scores: E(): 0, 80.1% identity in 216 aa overlap. Also similar to many bacterial histone-like DNA-binding proteins e.g. Bacillus stearothermophilus SW:DBH_BACST (P02346) (90 aa), Fasta scores: E(): 2e-09, 48.3% identity in 89 aa overlap. Note that the C-terminus is rich in the amino acids Ala, Val and Lys. Contains Pfam match to entry PF00216 Bac_DNA_binding, Bacterial DNA-binding protein. Contains PS00045 Bacterial histone-like DNA-binding proteins signature. |
| Functional category | Information pathways |
| Mutant | Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 2028724 | 2029326 | - |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium leprae TN|ML1683c|hupB
MNKAELIDVLTQKLGSDRRQATAAVENVVDTIVRAVHKGDSVTITGFGVFEQRRRAARVARNPRTGETVKVKPTSVPAFRPGAQFKAVVAGAQRLPLEGPAVKRGVATSAAKKAAIKKAPVKKALAKKAATKAPAKKAVKAPAKKITTAVKVPAKKATKVVKKVAAKAPVRKATTRALAKKAAVKKAPAKKVTAAKRGRK
Bibliography
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