Gene ML1688c in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namegltS
Gene length1509 bp
IdentifierML1688c
Location 2033591 bp
Protein summary information
Molecular mass55272.3 Da
Isoelectric point4.78
Protein length503 amino acids
Orthologs
M. tuberculosis H37RvRv2992c
M. lepromatosis Mx1-22AMLPM_1688
Cross-references
UniProtO33120
Gene OntologyCytoplasm, Glutamate-trna ligase activity, Glutamyl-trna aminoacylation, Atp binding
Enzyme Classification6.1.1.17
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE GLUTAMYL-TRNA SYNTHETASE GLTS (GLUTAMATE--TRNA LIGASE) (GLUTAMYL-TRNA SYNTHASE) (GLURS)
CommentsML1688c, len: 502 aa. Probable gltS, glutamyl-tRNA synthase (EC 6.1.1.17). Highly similar to many glutamyl-tRNA synthetases including: Bacillus subtilis SW:SYE_BACSU (P22250) (483 aa), Fasta scores: E(): 0, 37.4% identity in 486 aa overlap and Mycobacterium tuberculosis Rv2992c SW:SYE_MYCTU (O53241) (490 aa), Fasta scores: E(): 0, 81.4% identity in 488 aa overlap. Contains Pfam match to entry PF00749 tRNA-synt_1c, tRNA synthetases class I (E and Q).
Functional categoryInformation pathways
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS20335912035099-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML1688c|gltS
VTAVTSDGTPQAAKVRVRFCPSPTGVPHVGMVRTALFNWAYARHTGGTFVLRIEDTDADRDSEESYLALLDALRWLGLNWDEGPEVGGPYGPYRQSQRTDIYREVVAKLLATGEAYYAFSTPEEVENRHLAAGRNPKLGYDNFDRDLTDAQFSAYLAEGRKPVVRLRMPDEDISWDDLVRGTTTFAVGTVPDYVLTRASGDPLYTLVNPCDDALMKITHVLRGEDLLSSTPRQVALYQALIRIGMAERIPEFGHFPSVLGEGTKKLSKREPQSNLFAHRDRGFIPEGLLNYLALLGWAIADDHDLFSLDEMVAAFDVVDVNSNPARFDQKKADAVNAEHIRMLDSEDFAGRLRDYFTTHGYHIALDPANYEAGFVAAAQLVQTRIVVLGDAWDLLKFLNDDEYSIDSKAAAKELDADAGPVLDVACAVLDSLVDWTTASIEDVLKVALIEGLGLKPRKVFGPIRVAATGALVSPPLFESLELLGRARSLQRLSAARARVTSA
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