Gene ML1689c in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameML1689c
Gene length729 bp
IdentifierML1689c
Location 2035096 bp
Protein summary information
Molecular mass25673.6 Da
Isoelectric point5.04
Protein length243 amino acids
Structural information
PFAMPF01557, PF10370
Orthologs
M. tuberculosis H37RvRv2993c
M. lepromatosis Mx1-22AMLPM_1689
Cross-references
UniProtQ7AQ28
Gene OntologyMetabolic process, Hydrolase activity
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductPOSSIBLE 2-HYDROXYHEPTA-2,4-DIENE-1,7-DIOATE ISOMERASE (HHDD ISOMERASE)
CommentsML1689c, len: 242 aa. Possible 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase (EC 5.3.3.-). Similar to several putative 2-hydroxyhepta-2,4-diene-1,7-dioate isomerases including: Methanobacterium thermoautotrophicum TR:O27551 (EMBL:AE000911) (260 aa), Fasta scores: E(): 0, 51.9% identity in 216 aa overlap and Mycobacterium tuberculosis Rv2993c TR:O53242 (EMBL:AL021287) (239 aa), Fasta scores: E(): 0, 85.9% identity in 241 aa overlap. Contains Pfam match to entry PF01557 FAA_hydrolase, Fumarylacetoacetate (FAA) hydrolase family.
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS20350962035824-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML1689c|ML1689c
MFARELAEYPFGELTFTGRSWPLADVRLLAPMLASKVVCIGKNYADHIVEMGGQTGLASADPVIFLKPNTAIIGPNVPIRLPANASPVHFEGELALVVGRSCKDVPAVQAVDCILGYTIGNDMSARDQQRADGQWTRAKGHDTFCPVGPWIVTDLGPLDPADLELRTAVNGEVKQHSRTSLMIHGIGAIMEWISAVMTLLPGDLILTGTPAGVGPVEDGDIVSITVEGIGTLTNPVVRKGKS
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