Gene ML1695c in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameilvN
Gene length510 bp
IdentifierML1695c
Location 2043781 bp
Protein summary information
Molecular mass18284.2 Da
Isoelectric point7.52
Protein length170 amino acids
Structural information
PFAMPF01842, PF10369
Orthologues
M. tuberculosisRv3002c
Cross-references
UniProtO33113
Gene OntologyAmino acid binding, Branched-chain amino acid biosynthetic process, Acetolactate synthase activity
Enzyme Classification2.2.1.6
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE ACETOLACTATE SYNTHASE (SMALL SUBUNIT) ILVN (ACETOHYDROXY-ACID SYNTHASE) (AHAS) (ALS)
CommentsML1695c, len: 169 aa. Probable ilvN, acetolactate synthase small subunit (EC 4.1.3.18). Highly similar to many acetolactate synthases, small subunit, involved in valine and isoleucine biosynthesis, including: Mycobacterium avium SW:ILVH_MYCAV (Q59499) (167 aa), Fasta scores: E(): 0, 78.9% identity in 166 aa overlap and Mycobacterium tuberculosis Rv3002c SW:ILVH_MYCTU (O53249) (168 aa), Fasta scores: E(): 0, 83.5% identity in 164 aa overlap. Contains Pfam match to entry PF01842 ACT, ACT domain.
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS20437812044290-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML1695c|ilvN
MVGLPTHTLSVLVEDTPGVLARVAALFSRRGFNIESLAVGATECKTMSRMTIVVSAEETPLEQVTKQLHKLINVIKVVEQEADNSLSRELALIKVRAEAGTRSQVIEAVHLFRARVIDVSLESLTVEATGDCSKIEALLRVLEPFGVREIVQSGVVSLSRGPRGIGTVR
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