Gene ML1696c (ilvB1)
in Mycobacterium leprae TN
General annotation
| Type | CDS |
| Function | Unknown |
| Product | PROBABLE ACETOLACTATE SYNTHASE (LARGE SUBUNIT) ILVB (ACETOHYDROXY-ACID SYNTHASE) |
| Comments | ML1696c, len: 625 aa. Probable ilvB, acetolactate synthase I large subunit (EC 4.1.3.18). Highly similar to many acetolactate synthases, large subunit, involved in valine and isoleucine biosynthesis, including: Mycobacterium avium SW:ILVB_MYCAV (Q59498) (621 aa), Fasta scores: E(): 0, 82.7% identity in 624 aa overlap and Mycobacterium tuberculosis Rv3003c SW:ILVB_MYCTU (O53250) (618 aa), Fasta scores: E(): 0, 87.1% identity in 627 aa overlap. Contains Pfam match to entry PF00205 TPP_enzymes, Thiamine pyrophosphate enzymes. Contains PS00187 Thiamine pyrophosphate enzymes signature. |
| Functional category | Intermediary metabolism and respiration |
| Mutant | Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 2044342 | 2046219 | - |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium leprae TN|ML1696c|ilvB
VSAPTKPHARPQGAGNSVPNTVKPATQFPSKPAVAKLERVSPEQLTGAQSVIRSLEELDVEVIFGIPGGAVLLVYDPLFYSKKLRHVLVRHEQGAGHAASGYAHVTGKVGVCMATSGPGATNLVTPLADAQMDSVPVVAITGQVGRSLIGTDAFQEADISGITMPITKHNFLVRAGDDIPRVLAEAFHIASSGRPGAVLVDIPKDVLQGQCKFSWPPKMDLPGYKPNTKPHNRQIRAAAKLIADARKPVLYVGGGVIRGEATEQLRDLAELTGIPVVSTLMARGAFPDSHHQNLGMPGMHGTVAAVAALQRSDLLIALGTRFDDRVTGKLDSFAPDAKVIHADIDPAEIGKNRHADVPIVGDVKAVIVELIAMLRHYEVPGNIEMTDWWSYLDGVRKTYPLSYSPQSDGTLSPEYVIEKLGEIVGPEAVYVAGVGQHQMWAAQFISYEKPRTWLNSGGLGTMGFAIPAAMGAKIARPEAEVWAIDGDGCFQMTNQELATCAIEGAPIKVALINNGNLGMVRQWQALFYQERYSQTDLATHSHRIPDFVKLAEALGCVGLRCECEEDVVDVINQARAINNRPVVIDFIVGADAQVWPMVAAGASNDEIQAARGIRPLFDDESEGHV
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