Gene ML1733c in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameML1733c
Gene length828 bp
IdentifierML1733c
Location 2093457 bp
Protein summary information
Molecular mass30935.4 Da
Isoelectric point9.52
Protein length276 amino acids
Structural information
PFAMPF00440
Orthologs
M. tuberculosis H37RvRv3050c
M. lepromatosis Mx1-22AMLPM_1733
Cross-references
UniProtQ9CBQ1
Gene OntologySequence-specific dna binding transcription factor activity, Regulation of transcription, dna-dependent
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductProbable transcriptional regulatory protein tetR-family
CommentsML1733c, len: 275 aa. Probable transcriptional regulatory protein tetR-family. Similar to Mycobacterium tuberculosis Rv3050c TR:O53295 (EMBL:AL021287) (246 aa), Fasta scores: E(): 0, 86.6% identity in 238 aa overlap. Contains a putative helix-turn-helix motif situated between residues 79..100 (+3.98 SD). Contains a probable helix-turn-helix motif at aa 79-100 (Score 1407, SD +3.98) Contains Pfam match to entry PF00440 tetR, Bacterial regulatory proteins, tetR family.
Functional categoryRegulatory proteins
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS20934572094284-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML1733c|ML1733c
VTRRSIHTRKPLKWSGCAGQHVRSGKVFDVGRISLSYPSMKPGVKIDARSERWREHRKKVRGEIVDAAFRALDRLGPEVSVREIAEEAGTAKPKIYRHFTDKSDLFEAIGIRLRDMLWAAIFPAIDLATDSAREIIRRSVDEYVSLVDKHPNVLRVFIQGRFSAQSEATVRTLDEGREITLTMAEMFNNELREMELNRAASELAAFAAFGSVASATEWWLGPEPDSPRRMPREQFVAHLTIIMMAVIVGTAETLGISMNPDRPIHDAVPLDRSAS
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