Gene ML1755c in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namesdaA
Gene length1377 bp
IdentifierML1755c
Location 2129664 bp
Protein summary information
Molecular mass47779.3 Da
Isoelectric point4.78
Protein length459 amino acids
Structural information
PFAMPF03313, PF03315
Orthologs
M. tuberculosis H37RvRv0069c
M. lepromatosis Mx1-22AMLPM_1755
Cross-references
UniProtQ9CBP2
Gene OntologyL-serine ammonia-lyase activity, Gluconeogenesis, 4 iron, 4 sulfur cluster binding
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE L-SERINE DEHYDRATASE SDAA (L-SERINE DEAMINASE) (SDH) (L-SD)
CommentsML1755c, len: 458 aa. Probable sdaA, L-serine dehydratase (EC 4.2.1.13). Highly similar to many L-serine dehydratases including: Escherichia coli SW:TDCG_ECOLI (P42630) (454 aa), Fasta scores: E(): 0, 53.2% identity in 457 aa overlap and Mycobacterium tuberculosis Rv0069c SW:SDHL_MYCTU (O53614) (461 aa), Fasta scores: E(): 0, 69.2% identity in 461 aa overlap.
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS21296642131040-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML1755c|sdaA
MTISVFDLFTIGIGPSSSHTVGPMRAAARFVDGLAANGLLEDVCDIRVELFGSLAATGAGHGTMSAILLGLEGEHPERLDADDMVTRLACMRAAGTICLGGLIVIKFTEADVVLRPQTVLDRHPNAMTIVALARDGTKLAAETYYSVGGGFVVAHGDPPEGAEWTTGGVSFGSAGELLELAATRGMSICELMAEYEQSLRSEQEVRAGLLNIRDVMTQSVQRGIAQGGYLPGGLKVRRRAHSWHERLCAEDPNRDPVFAEDWVNLVALAVNEENAVGGRVVTAPTNGAAGIIPAVLHYAQHYCPAGRADPDDTSVRFLLTAGAIGSLYKELASISGAEVGCQGEVGSAASMAAAGLAEILGGTPAQVENAAEIAMEHSLGLTCDPIAGLVQIPCIERNAISAGKAINAARMAMRGDGTHRVSLDEVIATMRATGRDMNFKYKETAAGGLALAVNIVEC
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