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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
General annotation
TypeCDS
FunctionUnknown
ProductPossible transcriptional regulatory protein
CommentsML1783c, len: 322 aa. Possible transcriptional regulatory protein. Similar to M. tuberculosis Rv2258c TR:O53532 (EMBL:AL021925) (353 aa), Fasta scores: E(): 0, 65.2% identity in 273 aa overlap but shorter at N-terminus and frameshifted near C-terminus. Also similar to some C. elegans proteins e.g. TR:O01593 (EMBL:U97004) (365 aa), Fasta scores: E(): 7.5e-17, 25.1% identity in 303 aa overlap. Contains possible HTH motif at aa 7-28 (+3.24 SD). Contains a probable helix-turn-helix motif at aa 7-28 (Score 1191, SD +3.24)
Functional categoryRegulatory proteins
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS21591522160120-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
       
Protein sequence
>Mycobacterium leprae TN|ML1783c|ML1783c
MVGLSLVTSTQIAYVAGLNERYVREWLGDMTTGHVVDYYAETGTYSLSVHRVAVLVWATGTNNLASVAQFIPLFSGFEQQFIGGFCDDVGGPYSEFPRFYSLMAEMSGAMFDAAFVDVVLPLANGLPERLRSGAGVADFDCGSGHVVNVLVRAFPASWFIGIDFSNEAVAIHTAEEDRLGLGTVTFESHNLARLDKAAAYDVITVFDASHDHAQPVRVLENIYQALRPGDVLLMASIKVSSQLEDNVDVLMSIYLYTASLMHCMTVSLALQGAPDWMRCGEGGWPPRCSATRDWTTCGWSISSPTRSTTTYIYIATKLPRLT
      
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