Gene ML1783c in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameML1783c
Gene length969 bp
IdentifierML1783c
Location 2159152 bp
Protein summary information
Molecular mass35156.8 Da
Isoelectric point4.64
Protein length323 amino acids
Structural information
PFAMPF08242
Orthologs
M. tuberculosis H37RvRv2258c
M. lepromatosis Mx1-22AMLPM_1783
Cross-references
UniProtQ9CBN3
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductPossible transcriptional regulatory protein
CommentsML1783c, len: 322 aa. Possible transcriptional regulatory protein. Similar to M. tuberculosis Rv2258c TR:O53532 (EMBL:AL021925) (353 aa), Fasta scores: E(): 0, 65.2% identity in 273 aa overlap but shorter at N-terminus and frameshifted near C-terminus. Also similar to some C. elegans proteins e.g. TR:O01593 (EMBL:U97004) (365 aa), Fasta scores: E(): 7.5e-17, 25.1% identity in 303 aa overlap. Contains possible HTH motif at aa 7-28 (+3.24 SD). Contains a probable helix-turn-helix motif at aa 7-28 (Score 1191, SD +3.24)
Functional categoryRegulatory proteins
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS21591522160120-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML1783c|ML1783c
MVGLSLVTSTQIAYVAGLNERYVREWLGDMTTGHVVDYYAETGTYSLSVHRVAVLVWATGTNNLASVAQFIPLFSGFEQQFIGGFCDDVGGPYSEFPRFYSLMAEMSGAMFDAAFVDVVLPLANGLPERLRSGAGVADFDCGSGHVVNVLVRAFPASWFIGIDFSNEAVAIHTAEEDRLGLGTVTFESHNLARLDKAAAYDVITVFDASHDHAQPVRVLENIYQALRPGDVLLMASIKVSSQLEDNVDVLMSIYLYTASLMHCMTVSLALQGAPDWMRCGEGGWPPRCSATRDWTTCGWSISSPTRSTTTYIYIATKLPRLT
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