Gene ML1794 in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameML1794
Gene length1209 bp
IdentifierML1794
Location 2171519 bp
Protein summary information
Molecular mass43828.9 Da
Isoelectric point7.5
Protein length403 amino acids
Structural information
PFAMPF00155
Orthologs
M. tuberculosis H37RvRv2294
M. lepromatosis Mx1-22AMLPM_1794
Cross-references
UniProtQ9CBM9
Gene OntologyMethionine biosynthetic process, Pyridoxal phosphate binding, Transferase activity, transferring nitrogenous groups, Cystathionine beta-lyase activity
Enzyme Classification4.4.1.8
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductProbable aminotransferase
CommentsML1794, len: 402 aa. Probable aminotransferase (EC 2.6.1.-). Similar to M. tuberculosis predicted aminotransferase Rv2294 SW:YM94_MYCTU (Q50672) (407 aa), Fasta scores: E(): 0, 76.5% identity in 404 aa overlap, and to many others e.g. Escherichia coli MalY protein SW:MALY_ECOLI (P23256) (390 aa), Fasta scores: E(): 5.8e-27, 31.2% identity in 385 aa overlap. Also similar to ML2502 from M. leprae.
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS21715192172727+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML1794|ML1794
VTSNPLEQLTIEQLQCRTSMKWRAHPEDVLPLWVAEMDVLLAPTVAEAVHRAVDNGDTGYPYGTTFAEAISEFASQRWQWHDLDVSRTAIVPDVMLGVVEMLRLITDRGDGVIVSPPVYPPFYAFVTHDGRRVLEAPLGRDGRLDLAALQDAFSRARRSSGPNGKVAYLLCNPHNPTGSVHTVAELHGVAELARRFGVRVISDEIHAPLVLSGARFTPYLSIPGAENAFALMSATKGWNLCGLKAAIAIAGREAAADLRRIPKEVSHGPSHLGIIAHTAAFRTGSSWLDALLQGLEANRALLRDLVTKHLPGVRYQRPQGTYLTWLDCRHLGFDEQINEGLAAISDLSGPARWFLDHSRVALTSGHAFGTGGVGHVRVNFATSQAILIEALSRMGRALVNFR
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