Gene ML1807c
in Mycobacterium leprae TN
General annotation
| Type | CDS |
| Function | Unknown |
| Product | 3-OXOACYL-[ACYL-CARRIER PROTEIN] REDUCTASE FABG1 (3-KETOACYL-ACYL CARRIER PROTEIN REDUCTASE) (MYCOLIC ACID BIOSYNTHESIS A PROTEIN) |
| Comments | ML1807c, len: 253 aa. Probable fabG1, 3-oxoacyl-[ACP] reductase (EC 1.1.1.100). Similar to M. tuberculosis fabG Rv1483 SW:FABG_MYCTU (Q48930) (247 aa), Fasta scores: E(): 0, 68.6% identity in 245 aa overlap, and to many others e.g. Escherichia coli fabG 3-oxoacyl-[acyl-carrier protein] reductase SW:FABG_ECOLI (P25716) (244 aa), Fasta scores: E(): 0, 47.3% identity in 241 aa overlap. Also similar to ML1806, ML2565, ML1740, ML1094, ML0862, ML0135, ML0135, ML0429, ML2357, ML0108 and ML2059 from M. leprae. Contains Pfam match to entry PF00678 adh_short_C2, Short chain dehydrogenase/reductase C-terminus. Contains Pfam match to entry PF00106 adh_short, short chain dehydrogenase. Contains PS00061 Short-chain dehydrogenases/reductases family signature. |
| Functional category | Lipid metabolism |
| Mutant | Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 2187641 | 2188402 | - |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium leprae TN|ML1807c|fabG1
VTDAAAKVSAAPGRGKPAFVSRSILVTGGNRGIGLAVARRLVADGHRVAVTHRASVVPDWFFGVECDVTDNDAIGAAFKAVEEHQGPVEVLVANAGITSDMLIMRMSEEQFQKVIDVNLTGVFRVAKLASRNMIKQRFGRYIFMGSVVGLSGVPGQANYAASKSGLIGMARSLARELGSRSITANVVAPGFIDTEMTRAMDSKYQEAALQAIPLGRIGAVEEIAGAVSFLASEDAGYISGAVIPVDGGLGMGH
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