Gene ML1816c
in Mycobacterium leprae TN
General annotation
| Type | CDS |
| Function | Unknown |
| Product | PROBABLE MACROLIDE-TRANSPORT ATP-BINDING PROTEIN ABC TRANSPORTER |
| Comments | ML1816c, len: 545 aa. Possible macrolide-transport ATP-binding protein ABC transporter. Similar to M. tuberculosis Rv1473 TR:O53164 (EMBL:AL021184) (542 aa), Fasta scores: E(): 0, 87.9% identity in 545 aa overlap, and to many others e.g. Haemophilus influenzae hypothetical ABC transporter ATP-binding protein SW:YHES_HAEIN (P44808) (638 aa), Fasta scores: E(): 1.4e-30, 31.5% identity in 518 aa overlap. Also similar to ML1248, ML0669, ML0848, ML2189, ML1122, ML0114 and ML0336 from M. leprae. Contains 2 Pfam matches to entry PF00005 ABC_tran, ABC transporter. Contains 2 x PS00017 ATP/GTP-binding site motif A (P-loop). Contains 2 x PS00211 ABC transporters family signature. |
| Functional category | Cell wall and cell processes |
| Mutant | Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 2198962 | 2200599 | - |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium leprae TN|ML1816c|ML1816c
VITATDLEVRAGARILLSSDGPDLRVQPGDRIGLVGRNGAGKTTTLRILAGATEPYAGSVTWTGEIGYLPQDPKVGNLDVLARDRVLSARGLDVLLTDLEKQQALMAEVADDDARDRAIRRYGQLEERFLALGGYSAESEAGRICASLGLPERVLVQQLCTLSGGQRRRVELARILFAASRAGTGASGSGTTLLLDEPTNHLDADSLGWLRDFLRSHTGGLVVISHNVELIAAVVNRVWFLDAVLGKVDVYNMGWYKYLDSRATDEQRRRRERVNAERKATALRTQAAKMGAKATKAVAAQNMLRRADRMMAALDEERVIEKVAQIKFPTPAACGRTPLVAKGLSKTYGSLEVFTGVNLAIDRGSRVVVLGLNGAGKTTLLRVLAGAEKPDVGRLEPGHGLRIGYFAQEHDTLDNEDTVWQNIRHTAPEFGEQDLRGLLGAFMFSGPQLDQLAGTLSGGEKTRLALAGLVASTANVLLLDEPTNNLDPASRKQVLDALRNYQGAVVLVTHDPGAAKALDPQRVVLLPDGTEDYWSDEYRDLIELA
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