Gene ML1818c (trxB1) in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nametrxB
Gene length393 bp
IdentifierML1818c
Location 2201528 bp
Protein summary information
Molecular mass14428.5 Da
Isoelectric point7.68
Protein length131 amino acids
Structural information
PFAMPF00085
Orthologs
M. tuberculosis H37RvRv1471
M. lepromatosis Mx1-22AMLPM_1818
Cross-references
UniProtQ9CBL1
Gene OntologyCell redox homeostasis
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE THIOREDOXIN TRXB
CommentsML1818c, len: 130 aa. Probable trxB, thioredoxin. Similar to M. tuberculosis thioredoxin trxB1 Rv1471 TR:O53162 (EMBL:AL021184) (123 aa), Fasta scores: E(): 2.4e-25, 65.4% identity in 107 aa overlap, and M. tuberculosis thioredoxin trxA Rv1470 TR:O53161 (EMBL:AL021184) (124 aa), Fasta scores: E(): 1.6e-17, 47.0% identity in 117 aa overlap. Also similar to Escherichia coli thioredoxin 2 SW:THI2_ECOLI (P33636) (139 aa), Fasta scores: E(): 1.7e-07, 37.1% identity in 89 aa overlap. Also similar to ML2703 from M. leprae. Contains Pfam match to entry PF00085 thiored, Thioredoxin.
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS22015282201920-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML1818c|trxB
MVREHGVGVRRWTRRDLIAEQLNETINVNNMVLVAFWASWCGPDRLFVPTFHASSNKHSDVVHLNVDTKAERQLALAAQIRSIPTLVAFKKGKPLLSQAGDLTPAVPGYLVQQIKAFDVSDDGVVPDEQV
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