Gene ML1831c in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namemapA
Gene length801 bp
IdentifierML1831c
Location 2219409 bp
Protein summary information
Molecular mass27706.3 Da
Isoelectric point5.28
Protein length267 amino acids
Structural information
PFAMPF00557
Orthologues
M. tuberculosisRv0734
Cross-references
UniProtO33008
Gene OntologyMetalloexopeptidase activity, Proteolysis, Aminopeptidase activity
Enzyme Classification3.4.11.18
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE METHIONINE AMINOPEPTIDASE MAPA (MAP) (PEPTIDASE M) (MetAP)
CommentsML1831c, len: 266 aa. Probable mapA, methionine aminopeptidase (EC 3.4.11.18). Similar to M. tuberculosis methionine aminopeptidase mapA Rv0734 TR:O53797 (EMBL:AL021958) (266 aa), Fasta scores: E(): 0, 84.0% identity in 262 aa overlap, and to many others e.g. Bacillus subtilis methionine aminopeptidase SW:AMPM_BACSU (P19994) (248 aa), Fasta scores: E(): 0, 43.3% identity in 245 aa overlap. Also similar to ML1576 and ML0521 from M. leprae. Contains Pfam match to entry PF00557 Peptidase_M24, metallopeptidase family M24.
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS22194092220209-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML1831c|mapA
VGALTRLRSRRVVPQRSVGELDAMAAAGAVVAAALHAVRDAAGPGVSSLSLDEIAESVIREAGATPSFLRYHGYPATICTSVNDRVIHGIPSAVEILAPGDLVSIDCGAVLDGWHGDAAITFGVGTLTSVDEALSQATRESLEAGIAAMIVNNRLTDVAHAIEVSTRTSEIRYRLTFGIVQGYGGHGIGRHMHMDPFLPNEGAPGRGPLLVPGSVLAIEPMLTLGTGKTIVLDDEWTVTTADGSRAAHWEHTVAVTEDGPRVLTLA
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