Gene ML1833c in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namesecY
Gene length1317 bp
IdentifierML1833c
Location 2220763 bp
Protein summary information
Molecular mass47485.8 Da
Isoelectric point9.59
Protein length439 amino acids
Structural information
PFAMPF00344
Orthologs
M. tuberculosis H37RvRv0732
M. lepromatosis Mx1-22AMLPM_1833
Cross-references
UniProtO33006
Gene OntologyIntegral to membrane, Intracellular protein transmembrane transport, Plasma membrane, P-p-bond-hydrolysis-driven protein transmembrane transporter activity
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE PREPROTEIN TRANSLOCASE SECY
CommentsML1833c, len: 438 aa. Probable secY, preprotein translocase. Similar to M. tuberculosis preprotein translocase secy subunit Rv0732 SW:SECY_MYCTU (P94926) (441 aa), Fasta scores: E(): 0, 91.6% identity in 441 aa overlap, and to many others e.g. Bacillus subtilis SW:SECY_BACSU (P16336) (431 aa), Fasta scores: E(): 0, 42.7% identity in 445 aa overlap. Contains Pfam match to entry PF00344 secY, eubacterial secY protein. Contains PS00017 ATP/GTP-binding site motif A (P-loop). Contains PS00756 Protein secY signature 2.
Functional categoryCell wall and cell processes
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS22207632222079-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML1833c|secY
VLSAFISSLRTVDLRRKILFTLGILVLYRVSAALPSPGVNYRHVQQCIQEATAGEAGEIYSLINLFSGGALLKLTVGVMPYITASIIVQLLTVVIPRFEELRKEGQAGQAKMTQYTRYLAIALAVLQATSIVALAANGGLLQGCQEDIISDQSIFSLVVIVLVMTGGAALVMWMGELITERGIGNGMSLLIFVGIAARIPAEGKQILDSRGGVIFAAVCLAALVIIVGVVFVEQGQRRIPVQYAKRMVGRRMYGGTSTYLPLKVNQAGVIPVIFASSLIYIPHLITQLVRSGSGGVGKSWWDKFVGTYLSDPADPVYINIYFGLIIFFTYFYVSVTFNPDERADEMKKFGGFIPGIRPGRPTADYLRYVLSRITLPGSIYLGAIAVLPNLFLQIGNGGEVQNLPFGGTAVLIMIGVGLDTVKQIESQLMQRNYEGFLK
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