Gene ML1839c
in Mycobacterium leprae TN
General annotation
| Type | CDS |
| Function | Unknown |
| Product | POSSIBLE PROTEASE IV SPPA (ENDOPEPTIDASE IV) (SIGNAL PEPTIDE PEPTIDASE) |
| Comments | ML1839c, len: 602 aa. Possible protease IV, signal peptide peptidase (EC 3.4.21.-). Similar to M. tuberculosis protease IV, signal peptide peptidase Rv0724, TR:P95072 (EMBL:Z84395) (623 aa), Fasta scores: E(): 0, 80.2% identity in 602 aa overlap, and to many others e.g. Escherichia coli protease IV SW:SPPA_ECOLI (P08395) (618 aa), Fasta scores: E(): 2.3e-24, 33.1% identity in 531 aa overlap. Contains 2 Pfam matches to entry PF01343 Peptidase_U7, Peptidase family U7. |
| Functional category | Cell wall and cell processes |
| Mutant | Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 2226943 | 2228751 | - |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium leprae TN|ML1839c|sppA
MSAFLPPFPGIDDVRALANRVNTARHHGIPNGCVLEVNLRSLPPETTSFDPFTIITRGGRPMALREAVAAIHRAAADPRVAGMIARVQLGASPPAAVQELREAVATFSAVKPSLAWAETYPGTLSYYLASAFGEVWMQPSGSVGLVGFASNATFLRDVLAKVGIEAQFVARGEYKSAANLFTEGGFTDAHREAVSRMLESLQGQVWQGIAESRRIDPAALNPLADRAPLLRDDAVASGLVDRIGFRDEAYARIAELVGAESITPNSSEPQARTEANDGLPRLYLSRYASAGRSRLMPPMPLIPGRRSKPTVVVVTLEGPIVNGRGGPQFLPFGISTGGGDTIAAALREVAADDSVSAIVLRVNSPGGSVTASETIWREVKRARDRGKPVVVSMGAVAASGGYYVSVGADEIVANPGTITGSIGVITGKLVIRDLKGRLGVGSDTVRTNANADAWSANVPFTPEQHTHREAEADLCYADFLERVAEGRGMTTDAVDDVARGRIWTGADALERGLVDELGGLVTAVRRAKVLAGLDADVDVRIVSYPGSSLLDMVRPRASSQPGAASLPDAVATLLGRSVAGILEQVEQALSGVRVLWLGEYRF
Bibliography
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