Gene ML1878c in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namefusA1
Gene length2106 bp
IdentifierML1878c
Location 2257096 bp
Protein summary information
Molecular mass77128.4 Da
Isoelectric point4.9
Protein length702 amino acids
Structural information
PFAMPF00009, PF00679, PF03144, PF03764
Orthologues
M. tuberculosisRv0684
Cross-references
UniProtP30767
Gene OntologyGtpase activity, Cytoplasm, Translation elongation factor activity, Translational elongation, Gtp binding
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE ELONGATION FACTOR G FUSA1 (EF-G)
CommentsML1878c, len: 701 aa. Probable fusA1, elongation factor G. Similar to M. tuberculosis elongation factor G Rv0684 SW:EFG_MYCTU (O53790) (701 aa), Fasta scores: E(): 0, 90.3% identity in 701 aa overlap, and to many others e.g. Escherichia coli SW:EFG_ECOLI (P02996) (703 aa), Fasta scores: E(): 0, 59.2% identity in 703 aa overlap. Also similar to ML1498, ML0611, ML1877 and ML1556 from M. leprae. Contains Pfam match to entry PF00009 GTP_EFTU, Elongation factor Tu family. Contains Pfam match to entry PF00679 EFG_C, Elongation factor G C-terminus. Contains PS00301 GTP-binding elongation factors signature. Contains PS00017 ATP/GTP-binding site motif A (P-loop).
Functional categoryInformation pathways
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS22570962259201-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML1878c|fusA1
VAQKDVLTDLTKVRNIGIMAHIDAGKTTTTERILYYTGISYKIGEVHDGAATMDWMEQEQERGITITSAATTCFWNDNQINIIDTPGHVDFTVEVERSLRVLDGAVAVFDGKEGVEPQSEQVWRQADKYEVPRICFVNKMDKIGADFYFSVRTMQERLGANVIPIQLPVGSEGDFEGVVDLVEMKAKVWSTEAKLGEKYDVVGIPTDLQEKAEEYRTNLLETVAETDEALLEKYFSGEELTVAEIKGAIRKLTISSEAYPVLCGSAFKNKGVQPMLDAVIDYLPSPLDVPAAIGHVPGKEDEEIVRKPSTDEPLSALAFKVATHPFFGKLTYVRVYSGKVDSGSQVINATKGKKERLGKLFQMHSNKENPVETASAGHIYAVIGLKDTTTGDTLADPNNQIVLESMTFPDPVIEVAIEPKTKSDQEKLSLSIQKLAEEDPTFKVHLDSETGQTVIGGMGELHLDILVDRMRREFKVEANVGKPQVAYKETIRRVVETVEYTHKKQTGGSGQFAKVIIKLEPFSGENGATYEFENKVTGGRIPREYIPSVEAGARDAMQYGVLAGYPLVNLKVTLLDGAYHDVDSSEIAFKIAGSQVLKKAAAQAQPVILEPIMAVEVTTPEDYMGDVIGDLHSRRGQIQAMKERAGTRVVRAHVPLSEMFGYVGDLRSKTQGRANYSMVFNSYSEVPANVSKEIIAKATGE
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