Gene ML1878c
in Mycobacterium leprae TN
General annotation
| Type | CDS |
| Function | Unknown |
| Product | PROBABLE ELONGATION FACTOR G FUSA1 (EF-G) |
| Comments | ML1878c, len: 701 aa. Probable fusA1, elongation factor G. Similar to M. tuberculosis elongation factor G Rv0684 SW:EFG_MYCTU (O53790) (701 aa), Fasta scores: E(): 0, 90.3% identity in 701 aa overlap, and to many others e.g. Escherichia coli SW:EFG_ECOLI (P02996) (703 aa), Fasta scores: E(): 0, 59.2% identity in 703 aa overlap. Also similar to ML1498, ML0611, ML1877 and ML1556 from M. leprae. Contains Pfam match to entry PF00009 GTP_EFTU, Elongation factor Tu family. Contains Pfam match to entry PF00679 EFG_C, Elongation factor G C-terminus. Contains PS00301 GTP-binding elongation factors signature. Contains PS00017 ATP/GTP-binding site motif A (P-loop). |
| Functional category | Information pathways |
| Mutant | Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 2257096 | 2259201 | - |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium leprae TN|ML1878c|fusA1
VAQKDVLTDLTKVRNIGIMAHIDAGKTTTTERILYYTGISYKIGEVHDGAATMDWMEQEQERGITITSAATTCFWNDNQINIIDTPGHVDFTVEVERSLRVLDGAVAVFDGKEGVEPQSEQVWRQADKYEVPRICFVNKMDKIGADFYFSVRTMQERLGANVIPIQLPVGSEGDFEGVVDLVEMKAKVWSTEAKLGEKYDVVGIPTDLQEKAEEYRTNLLETVAETDEALLEKYFSGEELTVAEIKGAIRKLTISSEAYPVLCGSAFKNKGVQPMLDAVIDYLPSPLDVPAAIGHVPGKEDEEIVRKPSTDEPLSALAFKVATHPFFGKLTYVRVYSGKVDSGSQVINATKGKKERLGKLFQMHSNKENPVETASAGHIYAVIGLKDTTTGDTLADPNNQIVLESMTFPDPVIEVAIEPKTKSDQEKLSLSIQKLAEEDPTFKVHLDSETGQTVIGGMGELHLDILVDRMRREFKVEANVGKPQVAYKETIRRVVETVEYTHKKQTGGSGQFAKVIIKLEPFSGENGATYEFENKVTGGRIPREYIPSVEAGARDAMQYGVLAGYPLVNLKVTLLDGAYHDVDSSEIAFKIAGSQVLKKAAAQAQPVILEPIMAVEVTTPEDYMGDVIGDLHSRRGQIQAMKERAGTRVVRAHVPLSEMFGYVGDLRSKTQGRANYSMVFNSYSEVPANVSKEIIAKATGE
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