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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
General annotation
TypeCDS
FunctionUnknown
ProductPOSSIBLE RIBONUCLEOTIDE-TRANSPORT ATP-BINDING PROTEIN ABC TRANSPORTER MKL
CommentsML1892c, len: 338 aa. Possible mkl, ribonucleotide-transport ATP-binding protein ABC transporter. Similar to M. tuberculosis ABC transporter Rv0655 SW:MKL_MYCTU (O06784) (359 aa), Fasta scores: E(): 0, 93.2% identity in 336 aa overlap, and to many others e.g. Escherichia coli hypothetical ABC transporter ATP-binding protein SW:YRBF_ECOLI (P45393) (269 aa), Fasta scores: E(): 2.4e-32, 38.9% identity in 252 aa overlap. Also similar to ML0669, ML1424, ML1089, ML2352, ML2189, ML0336, ML1122, ML1113, ML0595, ML1114, ML0590, ML1726 and ML1816 from M. leprae. Contains Pfam match to entry PF00005 ABC_tran, ABC transporter. Contains PS00017 ATP/GTP-binding site motif A (P-loop). Contains PS00211 ABC transporters family signature.
Functional categoryCell wall and cell processes
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS22772672278283-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
       
Protein sequence
>Mycobacterium leprae TN|ML1892c|mkl
MPMGVAIEVKGLTKSFGSSRIWEDVTLDIPAGEVSVLLGPSGTGKSVFLKSLIGLLRPERGSILIDGTDIIECSAKELYEIRTLFGVLFQDGALFGSMNLYDNTAFPLREHTKKKESEIRDIVMEKLQLVGLGGDEKKFPGEISGGMRKRAGLARALVLDPQIILCDEPDSGLDPVRTAYLSQLIMDINAQIDATILIVTHNVNIARTVPDNMGMLFRKHLVMFGPREVLLTSDEPVVRQFLNGRRIGPIGMSEEKDESTMAEEAALLEAGHYAGGAEEVEGVPPQITVTPGMPKRKAVARRQARVRAMLPTLPKGAQAAILDDLEGAHNYQAHEFGD
      
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