Gene ML1929 in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namedef
Gene length594 bp
IdentifierML1929
Location 2312622 bp
Protein summary information
Molecular mass21143.9 Da
Isoelectric point4.98
Protein length198 amino acids
Structural information
PFAMPF01327
Orthologs
M. tuberculosis H37RvRv0429c
M. lepromatosis Mx1-22AMLPM_1929
Cross-references
UniProtQ9CBI2
Gene OntologyPeptide deformylase activity, Translation, Iron ion binding
Enzyme Classification3.5.1.88
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE POLYPEPTIDE DEFORMYLASE DEF (PDF) (FORMYLMETHIONINE DEFORMYLASE)
CommentsML1929, len: 197 aa. Probable def, polypeptide deformylase (EC 3.5.1.31). Similar to M. tuberculosis polypeptide deformylase Rv0429c SW:DEF_MYCTU (P96275) (197 aa), Fasta scores: E(): 0, 83.7% identity in 196 aa overlap, and to many others e.g Streptomyces coelicolor polypeptide deformylase SW:DEF_STRCO (Q9XAQ2) (208 aa), Fasta scores: E(): 5.9e-20, 43.8% identity in 176 aa overlap. Contains Pfam match to entry PF01327 Pep_deformylase, Polypeptide deformylase.
Functional categoryInformation pathways
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS23126222313215+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML1929|def
MAIAPIRIVGDPVLHTPTAPVQVAADGSLPANLNGLISTMYDTMDAAHGVGLAANQIGYGLRVFVYDCAEDCRQTARRRGVVINPILETSEIPETMPDPDTDNEGCLSVPGESFPIGRAQWARVTGLDADGNPVTTEGTGLFARMLQHETGHLDGFLYLDYLIGRHARSAKRAIKSRHWGVPGLSWMPGEVPDPFGP
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