Gene ML1938c in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namelytB2
Gene length1008 bp
IdentifierML1938c
Location 2324570 bp
Protein summary information
Molecular mass36509.6 Da
Isoelectric point6.43
Protein length336 amino acids
Structural information
PFAMPF02401
Orthologs
M. tuberculosis H37RvRv1110
M. lepromatosis Mx1-22AMLPM_1938
Cross-references
UniProtQ9X781
Gene Ontology4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase activity, Iron ion binding, Isopentenyl diphosphate biosynthetic process, mevalonate-independent pathway, Oxidation-reduction process, Terpenoid biosynthetic process, 3 iron, 4 sulfur cluster binding
Enzyme Classification1.17.1.2
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE LYTB-RELATED PROTEIN LYTB2
CommentsML1938c, len: 335 aa. Probable LytB2-related protein. Similar to M. tuberculosis LytB protein homolog lytB2 Rv1110 SW:LYB1_MYCTU (O53458) (335 aa), Fasta scores: E(): 0, 82.9% identity in 333 aa overlap, and to many others e.g. Escherichia coli LytB protein SW:LYTB_ECOLI (P22565) (316 aa), Fasta scores: E(): 0, 51.5% identity in 309 aa overlap.
Functional categoryCell wall and cell processes
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS23245702325577-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML1938c|lytB2
VKGMPPTVNMGIPGASRSIVENLKRKRVLLAEPRGYCAGVDRAVETVERSLRKYGPPVYVRHEIVHNRHVVETLERAGAVFVEETDYVPEGAIVIFSAHGVAPTVYAAAAERNLRTIDATCPLVTKVHNEVKRFARNDYDILLIGHEGHEEVIATAGEAPTHVQLVDGLAAVQQVVVRDENKVVWLSQTTLSVDETMRIVERLRQRFPKLQDPPSDDICYATQNRQVAVKAMAPECELVIVVGSRNSSNSVRLVEVAMGSGAGAAYLVDWAKDIDPAWLAGVTTVGVTSGASVPDILVQGVLKWLAERGYDVVQSVTTANEALVFALPREIRSAH
Bibliography
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