Gene ML1951c in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namephoH2
Gene length1302 bp
IdentifierML1951c
Location 2337626 bp
Protein summary information
Molecular mass46994.5 Da
Isoelectric point6.38
Protein length434 amino acids
Structural information
PFAMPF02562
Orthologs
M. tuberculosis H37RvRv1095
M. lepromatosis Mx1-22AMLPM_1951
Cross-references
UniProtQ9X792
Gene OntologyAtp binding
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE PHOH-LIKE PROTEIN PHOH2 (PHOSPHATE STARVATION-INDUCIBLE PROTEIN PSIH)
CommentsML1951c, len: 433 aa. Probable phoH2, PhoH-like protein. Similar to M. tuberculosis PhoH-like protein phoH2 Rv1095 TR:O53443 (EMBL:AL021897) (433 aa), Fasta scores: E(): 0, 92.8% identity in 432 aa overlap, and to others e.g. Escherichia coli PhoH-like protein YBEZ SW:PHOL_ECOLI (P77349) (359 aa), Fasta scores: E(): 1.1e-16, 31.2% identity in 276 aa overlap. Also similar to ML0627 from M. leprae. Contains PS00017 ATP/GTP-binding site motif A (P-loop).
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS23376262338927-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML1951c|phoH2
VTDIRTYVIDTSVLLSDPWACSRFAEHEVVVPLVVISELEAKRHHHELGWFARQALRLFDDLRLDHGRLDQPIPVGMQGGTLHVELNHSDPTVLPAGFRTDSNDSRILSCAANLAAEGRRVTLVSKDLPLRVKAAAVGLAADEYHAQDVVASGWSGMHEIETCAEDIDALFAEGKIDLGEARDLPCHTGIRLLGSNSHALGRVTAAKRVQLVRGDREVFGLRGRSAEQRVALDLLLDESVGIVSLGGKAGTGKSALALCAGLEAVLERRSHRKVVVFRPLYAVGGQELGYLPGSESEKMGPWAQAVFDTLEGLASPAVLEEVLSRSMLEVLPLTHIRGRSLHDSFVIVDEAQSLERNVLLTVLSRLGTGSRVVLTHDIAQRDNLRVGRHDGVAGVIEKLKGHPLFAHVTLQRSERSPVAALVTEMFEEIAGPH
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